Vibrational biospectroscopic study and chemical structure analysis of unsaturated polyamides nanoparticles as anti–cancer polymeric nanomedicines using synchrotron radiation

  • Authors

    • Alireza Heidari Faculty of Chemistry, California South University (CSU), Irvine, California, USA
    2018-08-04
    https://doi.org/10.14419/ijac.v6i2.12528
  • Unsaturated Polyamides Nanoparticles, Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) Spectroscopy, Carbon–Carbon Double Bond, Hardening–Cross Link, Cross Link, Raman Spectroscopy, Anti–Cancer Polymeric Nanomedicines, Synchrotron Radiati

  • Abstract

    Firstly, unsaturated polyamides nanoparticles were hardened by continuous synchrotron radiation and then, the induced changes in its chemical structure were studied by Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy. It was shown that applying synchrotron radiation for hardening not only leads to reduction of hardening time but also creates cross link in polymer by breaking Carbon–Carbon double bond, without any considerable change in its chemical structure. In addition, an unsaturated polyamide nanoparticle as anti–cancer polymeric nanomedicines is hardened by synchrotron radiation. Its chemical structure before and after hardening is studied using Raman and Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy. The results show that Raman spectroscopy is considerably better than Attenuated Total Reflection–Fourier Transform Infrared (ATR–FTIR) spectroscopy in detecting the changes happened in chemical structure.

     

     

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    Heidari, A. (2018). Vibrational biospectroscopic study and chemical structure analysis of unsaturated polyamides nanoparticles as anti–cancer polymeric nanomedicines using synchrotron radiation. International Journal of Advanced Chemistry, 6(2), 167-189. https://doi.org/10.14419/ijac.v6i2.12528

    Received date: 2018-05-06

    Accepted date: 2018-07-17

    Published date: 2018-08-04