Evaluation of retardant property of green hair growth retardant formula
Keywords:Depilatory Cream, Extracts, Phytochemicals, Retarding Property, Toxicity.
Background: The relevance of depilatory creams has appreciated significantly in recent time and their demand is on the increase. However most commercial depilatory creams contain chemicals with questionable health safety. These synthetic chemicals cause scaring, itching and burns on the skin.
Objectives: The study attempted to formulate green hair growth retarding cream, testing the formula for phytochemicals, hair growth retarding property and toxicity.
Methods: the cream was formulated from extracts of Tumeric (Curcuma longa), Aloe vera (Aloe barbadensis miller), Guava (Psidium guajava) and Neem (Azadirachta indica), evaluated for its phytochemical constituents and tested for its hair growth retardant property and toxicity on mice.
Results: The results show the presence of phytochemicals like tannins, phenols, flavonoids, terpeniods, alkaloids, volatile oil, anthroquinone, glycosides, saponins and a 25% hair growth retarding efficiency on tested mouse, no signs of itching, redness, swelling and topical injuries on the mouse.
Conclusion: overall, the research therefore provide convincing evidence of the safety of the formula over the conventional ones and also exhibit satisfactory hair regrowth retarding property.
 Postajian M. (2011): Cold wax depilatory composition and related process. United State Patent, US 7 867, 289, B2
 Schlossman M. (2008) chemistry and manufacture of cosmetics, Science, 4th edition, Allure Publishing. 724
 Schueller R. (2009): Beginning Cosmetic Chemistry, second edition. Allure Publishing. 531
 Nanda S, Nanda A, Khar K. R. (2006): Cosmetic Technology, Birla Publication Pvt. Ltd., 388
 Laura Nwalsial. (2013): Say Goodbye to Annoying Hair & Hello to Smooth Skin!. What You Need to Know About Hair Removal. Bella naija, Retrieved 13th March, 2016 from http://www.bellanaija.com/2013/07/say-goodbye-to-annoying-hair-hello-to-smooth-skin-what-you-need-to-know-about-hair removal/
 Depilatories, Cosmetics and Toiletories. (1990): (105), 87-89.
 Chemistry in your cupboard/ veet. Nucleophilic attack by S in RS on an S atom in cystine. 2013. Retrieved 21st December 2016 from http://www.rsc.org/learn-chemistry/resources/chemistry-in-your-cupboard/veet/1
 Seema, E. (2008): Isolation and Identification of Cyaniding Pigment from Allium Cepa L. and its Application as Antioxidant. M.Sc Thesis. University of Basra.
 Alupuli, A., Calinescu, I., Lavric, V. (2009): Ultrasonic vs Microwave Extraction Intensification of Active Principles from Medicinal Plants. AIDIC Conference Series, 09; 1-8DOI: 103303/ ACOS0909001.
 Ashutush Kar. (2003): Pharmacognosy and Pharmacobiotechnology. New age international, K. K. Gutpa: New Delhi.
 Bartram, T. (1995): Encyclopedia of Herbal Medicine, 1st ed; Grace Publishersâ€™ Bournemouth.
 Trease, G. E. Evans, W. C. (1989): Pharmacognosy, 11th ed; Brailliar Tirideland Mac Millian Publisherssâ€™ London.
 Lecture Demostration manual general chemistry. Identification of phenols-ferric chloride test. University of Colorado
 Neelam V, Rupinder K. Sohal, Rajiv Gupta, Shubbini A. Saraf. (2011): Formulation and Evaluation of Herbal Depilatory Cream. Pharmacologyonline. 3, 674-683.
 Wakisaka, E. Kitahara, T. Tsuji, N. Kusuoku, H. (2009). Herbal hair growth inhibitor and depilation accelerator. United State Patent US 7,488,499B2.
 Igbinosa, O. O. Igbinosa, E. O. Aiyegoro, O. A. (2009). Antimicrobial activity and Phytochemical screening of stem bark extracts from jatropha curcas (linn). African Journal Pharm. and pharmacol. 3(2): 058-062.
 Hussain, J. A. L. Khan, N. Rehman, M. Hamayun, Z. K. Shinwari, W. Malik, I. J. L. (2009). Assessment of herbal products and their composite medicinal plants through proximate and micronutrients analysis. Journal. Med. Pl. Res. 3(12): 1072-1077.
 Jouad, H. Lacalle-Duboi, M. A. Lyoussi, B. Eddouks, M. (2001): Effect of flavonoids extracted from Spergularia purpurea pers on arterial blood pressure and renal function in normal and hypertensive rats. J. ethnopharmacol, 76(2): 159-163. https://doi.org/10.1016/S0378-8741(01)00209-4.