The anticancer potential of various substituted pyridazines and related compounds

  • Authors

    • Mohammad Asif GRD(PG)IMT, RAJPUR, DEHRADUN
    2014-09-15
    https://doi.org/10.14419/ijac.v2i2.2661

  • Abstract

    Pyridazine nucleus exhibited immense pharmacological activities. Pyridazine nucleus is present in various compounds that possess remarkable pharmacological activities. Various pyridazinone compounds have antitumor activity. Some of them pyridazinone derivatives bearing different moieties were exhibited excellent anticancer activity toward human cancer cell lines. They showed remarkable activity against leukemia, non-small cell lung cancer, colon, central nervous system, melanoma, ovarian and breast cancer cell lines. These compounds were act by different mechanism.

    Keywords: Pyruvate Kinase; Anti-Cancer; Pyridazines; Biological Activities; Cytotoxicity.

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  • How to Cite

    Asif, M. (2014). The anticancer potential of various substituted pyridazines and related compounds. International Journal of Advanced Chemistry, 2(2), 148-161. https://doi.org/10.14419/ijac.v2i2.2661

    Received date: 2014-05-02

    Accepted date: 2014-05-31

    Published date: 2014-09-15