High performance liquid chromatography quality control


  • M. Mohammed El Amine Laboratory of Electrochemistry and Chemical Physics, Faculty of Sciences and Technologies, Mohammedia
  • A. E. Ghanjaoui
  • A. Mandil
  • A. Ait Sidi Mou
  • R. Slimani






HPLC, Analytical method, Validation, Development, Quality Control.


This review gives a general overview of High Performance Liquid Chromatography (HPLC) Method for the detection, the separation and the quantification of the active compounds from the organics matrices. A brief description of the instrumentation and the method devel-opment is provided. The principles of HPLC including different separation modes and detection methods for the quantitative analysis are summarized. Finely, the validation procedures in real samples are also described.




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