Molecular interaction on imidazolium based ionic liquids and serum albumin: A spectroscopy approach


  • Manoj Kumar Banjare MATS School of Sciences, MATS University, Pagaria Complex, Pandri, Raipur, C.G. 492009, India
  • Ramesh Kumar Banjare MATS School of Sciences, MATS University, Pagaria Complex, Pandri, Raipur, C.G. 492009, India
  • Kallol Kumar Ghosh Pt. Ravishankar Shukla University, Raipur, C.G., India



FTIR, Fluorescence, Ionic Liquids, Serum Albumin, Complexation.


Interaction between globular proteins with imidazolium based ionic liquids (ILs) is extremely significant considering that of the vast use of ILs, since protein stabilizer in the current years. The present work, the interaction of human serum albumin (HSA) and bovine serum albumin (BSA) with 1-butyl-3-methylimidazolium octylsulphate (BmimOS) and 1-decyl-3-methylimidazolium tetrafluoroborate (DmimBF4) have been examine the use of fluorescence and FTIR. Fluorescence spectra of HSA/BSA are extinguished by BmimOS /DmimBF4 ILs by way of the dynamic method. The various thermodynamic parameters were revealing that very susceptible interactions exist between HSA/BSA and BmimOS /DmimBF4. The conformational adjustments of HSA/BSA were observed by means of FTIR analysis. Fluorescence methods were completed to find out about the thermal balance of HSA/BSA at different temperature. The thermal balance of BSA in the presence of ILs follows the style BmimOS/DmimBF4 and presence of extra hydrophobic IL, decay increases swiftly as a characteristic of concentration.



Author Biography

Manoj Kumar Banjare, MATS School of Sciences, MATS University, Pagaria Complex, Pandri, Raipur, C.G. 492009, India

Dr. Manoj Kumar Banjare obtained his Ph.D. from Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India on the topic effect of ionic liquids on the micellar system and nanomaterials under the supervision of Prof. Kallol K. Ghosh. His qualified Junior Research Fellowship (JRF)/ Lectureship (LS) National Eligibility Test (NET) and Graduate Aptitude Test in Engineering (GATE) examination. He is currently working as a Assistant Professor in MATS School of Sciences department, MATS University Raipur, (C.G.) India. He is a recipient of the Young Scientist Award (Professor Santi Ranjan Palit Memorial Award) for 2019 years from the Indian Chemical Society of India (56th Annual Convention of Chemist 2019 & International Conference on Recent Trend in Chemical Sciences ). His research is focused on surface chemistry, ionic liquids, deep eutectic solvents, nanomaterials, self assembly of cyclodextrins and physicochemical properties of surfactants. He has published more than 17 papers in reputed journals viz America Chemical Society (ACS), Royal society of chemistry (RSC), Elsevier, Springer and wiley.


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