Comparative study of efficacy of commercial anthelmintic response against gastrointestinal nematodes in goats of Jhenidah district, Bangladesh
-
2019-12-15 https://doi.org/10.14419/ijbr.v7i1.29777
-
Parasitic Disease, Goat, Anthelmintic, Fecal Eggs and Efficacy. -
Abstract
Background: Parasitic disease constitutes 60-70% diseases affecting the animals and has serious economic implication in livestock entrepreneurship by direct and indirect production loss. Indiscriminate use of anthelmintic drugs has made the situation even more precarious. A similar problem was encountered in goat from Holidhani, Jhenidah, where goats with complain of intermittent diarrhea and loss of body condition was reported despite of routine deworming.
Objective:Â Determining the efficacy of conventional anthelmintics used and its comparison with some unexploited antiparasitic drugs for the same reason.
Methods: Sixty-five goats were divided into five groups. Group A goats were kept as the control, Group B (I, II, III), group C (IV, V, VI), group D (VII, VIII, IX) and group E (X, XI, XII) goats were treated with levamisole, albendazole, fenbendazole and ivermectin respectively. All the treated and control goats were kept, housed for 21 days after the first treatment. Fecal samples were collected and counted on 1st, 7th, 14th and 21st day by using McMaster counting method.
Results: Among the three doses of levamisole, albendazole, fenbendazole and ivermectin, the doses of 7.5, 7.5, 5.0 and 0.2 mg/kg body weight, body weight were found to be most effective against gastrointestinal nematodes in goats with a maximum reduction of fecal egg count to the extent of 95.38, 97.13, 98.08 & 99.16 percent respectively.
Conclusion: The study revealed low efficacy of levamisole and hence ivermectin is a better drug than albendazole and fenbendazole to control gastrointestinal nematodes in goats.
Â
-
References
[1] Akhter N, Mirbahar KB, Jatoi SA, Bhutto B & Mirani AH (2016) Efficacy of Valbazen (Albendazole) against gastrointestinal Nematodes in goats. Pakistan Journal of Agriculture, Agricultural Engineer and Veterinary Science 32 (2): 277-283.
[2] Ali S, Anwar AH, Hayat B, Iqbal Z & Hayat CS (1997) Field Evaluation of Anthelmintic Efficacy of Levamisole, Albendazole, Ivermectin and Morantel Tartrate against gastrointestinal nematodes of sheep. Pakistan Veterinary 17 (3).
[3] Amin MR, Husain SS & Islam ABMM (2001) Reproductive peculiarities and litter weight in different genetic groups of Black Bengal does. Asian-Australian Journal of Animal Science 14(3): 297-301.
[4] BARC Bangladesh (2010). Agricultural Research Priority: Vision-2030 and Beyond (Sub-sector: Livestock). Bangladesh Agriculture Research Council, Farmgate, Dhaka.
[5] Buttar BS, Rai HS, Singh NK, Jyoti HM & Rath S (2012) Emergence of anthelminthic resistance in an organized sheep farm in Punjab. Journal of Veterinary Parasitology 26(1):69-71.
[6] Byaruhanga C & Okwee-Acai J (2013) Efficacy of albendazole, levamisole and ivermectin against gastro-intestinal nematodes in naturally infected goats at the National Semi-arid Resources Research Institute, Serere, Uganda. Veterinary Parasitology. Volume 195. Issue 1-2, 183-186. https://doi.org/10.1016/j.vetpar.2013.01.007.
[7] Coles GC, Bauer C, Borgsteede FHM, Greats S, Klei TR & Taylor MA (1992) World Association for the Advancement of Veterinary Parasitology (WAAVP) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet. Parasitol., 44: 35- 44. https://doi.org/10.1016/0304-4017(92)90141-U.
[8] FAO (1999) Opportunities for incorporating genetic elements into the management of farm animal diseases: policy issues, by S. Bishop, M. de Jong & D. Gray. Background Study Paper No. 18. Commission on Genetic Resources for Food and Agriculture. Rome (available at ftp://ftp.fao.org/docrep/fao /meeting /015 /aj629e. pdf).
[9] Gathuma J, Gachuiri M & Omore A (2007) Risk factors of gastrointestinal nematode parasite infections in small ruminants kept in smallholder mixed farms in Kenya. BMC Veterinary Research 3:1. https://doi.org/10.1186/1746-6148-3-1.
[10]Godara R, Sharma RL & Sodhi SS (2011) Efficacy of fenbendazole, levamisole and ivermectin against gastrointestinal nematodes in Jamunapari goats. Journal of Parasitic Diseases 35(2):219-21. https://doi.org/10.1007/s12639-011-0052-5.
[11]Haq S & Shaikh H (1968) A Survey of Helminth Parasitsing the Gastro-intestinal Tracts of Goats and Sheep in East Pakistan. East Pakistan Journal of Veterinary Science 2(2): 54-62.
[12] Hasan MJ, Ahmed JU & Alam MM (2014) Reproductive performances of Black Bengal goat under semi intensive and extensive conditions at rural areas in Bangladesh. Journal of Advance in Veterinary and Animal Research 1(4): 196-200. https://doi.org/10.5455/javar.2014.a37.
[13]Hassan MM, Hoque MA, Islam SKMA, Khan SA, Roy K, Banu Q. A (2011) prevalence of parasites in Black Bengal goats in Chittagong, Bangladesh. International Journal of Livestock Production 2:40–44.
[14]Hossain MJ, Amin M, Mostofa M, Sharif Khalid SMA (2004). Efficacy of levanid against natural gastrointestinal nematodiasis and paramphistomiasis in sheep. Bangladesh Veterinary Journal 21:70–73.
[15]Husain SS (1993) A study on the productive performance and genetic potentials of Black Bengal goats. A Ph.D. Thesis, Bangladesh Agricultural University, Mymensingh.
[16]Islam KB & Taimur MJFA (2008). Helminthic and protozoan internal parasitic infections in free ranging small ruminants of Bangladesh. Slovenian Veterinary Researcher 45: 67–72.
[17]Islam MM, Islam MA, Rahman MM, Howlader & Lucky N (2015) Prevalence of Gastrointestinal Nematodiasis and Comparative Efficacy of Anthelmintics on Body Weight of Cattle in Bangladesh. International Journal of Scientific Research in Agricultural Sciences 2(3): 061-075. https://doi.org/10.12983/ijsras-2015-p0061-0075.
[18]Kennedy TJ & Todd AC (1975) Efficacy of Fenbendazole against gastrointestinal parasites of sheep. American Journal of Veterinary Research 36(10):1465-7.
[19]Keyyu JD, Mahingika HM, Magwisha HB & Kassuku AA (2002) Efficacy of Albendazole and Levamisole against Gastrointestinal Nematodes of Sheep and Goats in Morogoro, Tanzania. Tropical Animal Health and Production 34(2): 115–120. https://doi.org/10.1023/A:1014214122167.
[20]Khajuria JK (2010) Studies on epidemiology and resistance against benzimidazoles in gastrointestinal nematodes of small ruminants, PhD thesis submitted to SKUAST-J, Jammu, 1-69.
[21] Livestock Economy (2017) Department of Livestock Services, Bangladesh.
[22]Mbuh JV, Ndamukong KJ, Ntonifor N & Nforlem GF (2008) Parasites of sheep and goats and their prevalence in Bokova, a rural area of Buea Sub Division, Cameroon. Veterinary Parasitology 156:350–352. https://doi.org/10.1016/j.vetpar.2008.06.021.
[23]Mohanta UK, Anisuzzaman A, Farjana T, Das PM, Majumder S and Mondal MMH (2007) Prevalence, population dynamics and pathological effects of intestinal helminths in Black Bengal goats. Bangladesh Journal of Veterinary Medicine 5:63–69. https://doi.org/10.3329/bjvm.v5i1.1313.
[24]Mondal MMH, Islam MK, Hur J, Lee JH & Baek BK (2010) Examination of gastrointestinal helminth in livestock grazing in grassland of Bangladesh. The Korean Journal of Parasitology 38:187–190. https://doi.org/10.3347/kjp.2000.38.3.187.
[25] Morand-Fehr P & Boyazoglu J (1999) Present state and future look of the small ruminant sector. Small Ruminant Research 34:175-188. https://doi.org/10.1016/S0921-4488(99)00071-1.
[26]Oyeduntan A & Uwalaka EC (2015) Effectiveness Evaluation of Levamisole, Albendazole, Ivermectin, and Vernonia amygdalina in West African Dwarf Goats. Journal of Parasitology Research Volume. Article ID 706824, 5 pages. https://doi.org/10.1155/2015/706824.
[27]Pinkrah R (2017) The efficacy of Albendazole against gastrointestinal nematodes in naturally Infected sheep and goats on three different farming systems in Ghana. Research · November 2017.
[28]Poddar PR, Begum N, Alim MA, Dey AR, Hossain MS & Labony SS (2017) Prevalence of gastrointestinal helminths of sheep in Sherpur, Bangladesh. Journal of Advanced Veterinary and Animal Research. 4:274–280. https://doi.org/10.5455/javar.2017.d224.
[29]Qadir ANMA (1967) Investigation on the incidence of gastrointestinal parasites of goats in the East Pakistan Agricultural University Campus. Bangladesh Veterinary Journal 15(2): 58-61.
[30]Ram H, Rasool TJ, Sharma AK, Meena HR & Singh SK (2007) Comparative efficacy of different anthelmintics against fenbendazole resistant nematodes of pashmina goats. Veterinary Research and Communication 31: 719-723. https://doi.org/10.1007/s11259-007-0021-8.
[31] Raza MA, Younas M & Schlecht E (2014) Prevalence of gastrointestinal helminths in pastoral sheep and goat flocks in the Cholistan desert of Pakistan. The Journal of Animal & Plant Sciences. 24:127– 134.
[32]Rialch A, Vatsya S & Kumar RR (2013) Detection of benzimidazole resistance in gastrointestinal nematodes of sheep and goats of sub himalyan region of northern India using different tests. Veterinary Parasitology 198: 312-318. https://doi.org/10.1016/j.vetpar.2013.09.018.
[33]Tramboo SR, Shasardar RA, Allaie IM, Wani ZA & Abbas M (2017) Efficacy of ivermectin, closantel and fenbendazole against gastrointestinal nematodes of sheep in Kashmir valley. Journal of Parasitic Diseases 4(2): 380–382. https://doi.org/10.1007/s12639-016-0810-5.
[34]Sangma A, Begum N, Roy BC & Gani MO (2012) Prevalence of helminth parasites in sheep (Ovis aries) in Tangail district, Bangladesh. Journal of the Bangladesh Agricultural University 10: 235–244. https://doi.org/10.3329/jbau.v10i2.14913.
[35]Sharma P, Sharma D, Dogra PK & Mandial RK (2014) Comparative efficacy of fenbendazole and oxyclozanide-tetramisole combination against gastrointestinal nematodes in naturally infected Gaddi goats. Veterinary Research International 2(1): 15-17.
[36] Sharma S, Kumar S, Farooq J & Katoch R (2015) Comparative Study of Efficacy of Fenbendazole and Ivermectin against Haemonchus contortus in Goats of Jammu region. Journal of Animal Research 5(2): 293-295. https://doi.org/10.5958/2277-940X.2015.00050.9.
[37]Silvestre A, Leignel V, Berrag B, Gasnier N, Humbert JF, Chartiere C & Cabaret J (2002) Sheep and goat nematode resistance to anthelmintics: pros and cons among breeding management factors. Veterinary Research 33: 465-80. https://doi.org/10.1051/vetres:2002033.
[38]Teklemariam T, Fantahun T, Alemayehu B & Beyene A (2016). Efficacy of selected anthelmintics against gastrointestinal nematodes on naturally infected small ruminants in Gimbo district, Kaffa Zone, South West Ethiopia. Livestock Research for Rural Development, 28 (12).
[39]United Nations (2011). Department of Economic and Social Affairs, Population Divition: World population Prospects: The 2010 Revision. New York.
[40]Wolstenholme AJ, Fairweather I, Prichard R & Samson V (2004) Drug resistance in veterinary helminthes. Trends in Parasitology 20:469–476. https://doi.org/10.1016/j.pt.2004.07.010.
-
Downloads
-
How to Cite
Kumar Halder, P., Kumar Sarker, B., Shah Alam, M., Nime, J., Tareq Mussa, M., Mostafijur Rahman, M., Kumer Chakraborty, B., & Harun-ur-Rashid, S. (2019). Comparative study of efficacy of commercial anthelmintic response against gastrointestinal nematodes in goats of Jhenidah district, Bangladesh. International Journal of Biological Research, 7(1), 14-18. https://doi.org/10.14419/ijbr.v7i1.29777Received date: 2019-08-21
Accepted date: 2019-09-26
Published date: 2019-12-15