Clinicopathological correlation of odontogenic cysts and tumours in a South Indian population over a 20-year period

  • Authors

    • Niranjan K C Reader, Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences and Hospital, Dharwad
    • Zulfin Shaikh Postgraduate student, Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences and Hospital, Dharwad
    2014-03-04
    https://doi.org/10.14419/ijdr.v2i2.1590
  • Of several studies carried out worldwide, there is limited data available on the combined prevalence of odontogenic cysts and tumours in the Indian sub-continent. This study was designed to determine the prevalence of these lesions in the region of North Karnataka, South India over a period of 20 years. Histologically diagnosed cases of odontogenic cysts and tumours were reviewed from January 1989 to December 2008 and analyzed for age, gender and anatomical location and subjected to one way ANOVA and post Hoc statistical tests. 10.3% were odontogenic cysts and 2.13% were odontogenic tumours. Radicular cyst (50.8%) was the most common odontogenic cyst. Odontogenic cysts were frequent in males (63%) and anterior region of maxilla (54.4%) with a mean age of 27.8 years. The most common odontogenic tumour was Ameloblastoma (54.8%). Odontogenic tumours showed predilection for females (51%) and posterior region of mandible (68.4%) with a mean age for 29.9 years. Demographic profile of these lesions shows a distinct geographic variation.

     

    Keywords: Demographic profile, geographic variation, North Karnataka, odontogenic cysts, odontogenic tumours.

  • References

    1. Ahlfors E, Larsson A, Sjögren S (1984) The Odontogenic keratocyst: A benign cystic tumor. Journal of Oral Maxillofacial Surgery 42, 10-19.
    2. Arotiba JT, Lawoyin JO, Obiechina AE (1998) Pattern of occurrence of odontogenic cysts in Nigerians. Eastern African Medical Journal 75, 664-666.
    3. Avelar RL, Antunes AA, Carvalho RW, Bezerra PG, Neto PJ, Andrade ES (2009) Odontogenic cysts; a clinicopathological study of 507 cases. Journal of Oral Science 51,581–6.
    4. Avelar RL, Antunes AA, Santos T, Andrade E, Dourado E (2008) Odontogenic tumors: clinical and pathological study of 238 cases. Revista Brasileira de Otorrinolaringologia 74,668-73.
    5. Bataineh AB, Rawashdeh MA, Al Qudah MA (2004) The prevalence of inflammatory and developmental odontogenic cysts in a Jordanian population: A clinicopathologic study. Quintessence International 35,815–9.
    6. Bento PM, Souza LB, Pinto LP (1996) Estudo epidemiologico dos cistos odontogenicos: analise de 446 casos. Revista Odonto Ciência 11,125-42.
    7. Borges LB, Fechine FV, Mota MRL, Sousa FB, Alves APNN (2012) Odontogenic lesions of the jaw: a clinical-pathological study of 461 cases. Revista Gaúcha de Odontologia Destaques 60, 71-78.
    8. Camisasca DR, Janini MER, Silva Junior JA, Bernardo V (2005) Cistos e tumores odontogenicos: estudo epidemiologico. Revista da Associação Paulista de Cirurgiões Dentistas 59,261-6.
    9. Cankurtaran CZ, Branstetter BF, Chiosea SI, Barnes EL (2010) Ameloblastoma and Dentigerous Cyst Associated with Impacted Mandibular Third Molar Tooth. Radio Graphics 30, 1415–1420.
    10. de Souza LB, Núñez MAG, Nonaka CFW, De Medeiros MC, Torres TF, Emiliano GBG (2010) Odontogenic cysts: Demographic profile in a Brazilian population over a 38-year period. Medicina Oral Patologia Oral y Cirugia Bucal 15,583-90.
    11. Daley TD, Wysocki GP, Pringle GA (1994) Relative incidence of odontogenic tumors and oral and jaw cysts in a Canadian population. Oral Surgery Oral Medicine Oral Pathology 77,276-80.
    12. Das S, Das AK (1993) A review of pediatric oral biopsies from a surgical pathology service in a dental school. Pediatric Dentistry 15,208–11.
    13. Dong Q, Pan S, Sun LS, Li TJ (2010) Orthokeratinized Odontogenic Cyst: A Clinicopathologic Study of 61 Cases. Archives of Pathology & Laboratory Medicine 134, 271–275.
    14. Gill S, Chawda J, Jani D (2011) Odontogenic tumors in Western India (Gujarat): Analysis of 209 cases. Journal of Clinical and Experimental Dentistry 3, 78-83.
    15. Guerrisi M, Piloni MJ, Keszler A (2007) Odontogenic tumors in children and adolescents. A 15-year retrospective study in Argentina. Medicina Oral Patologia Oral y Cirugia Bucal 12,180-5.
    16. Gultelkin SE, Tokman B, Turkseven MR (2003) A review of paediatric oral biopsies in Turkey. International Journal of Dentistry 53, 26–32.
    17. Jones AV, Craig GT, Franklin CD (2006) Range and demographics of odontogenic cysts diagnosed in a UK population over a 30-year period. Journal of Oral Pathology and Medicine 35,500–7.
    18. Kreidler JF, Raubenheimer EJ, van Heerden WF (1993) A retrospective analysis of 367 cystic lesions of the jaw-the Ulm experience. Journal of Craniomaxillofacial Surgery 21,339-41.
    19. Ladeinde AL, Ajayi OL, Ogunlewe MO, Adeyemo WL, Arotiba GT, Bamgbose BO (2005) Odontogenic tumors: A review of 319 cases in a Nigerian teaching hospital. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 99,191-5.
    20. Lawal AO, Adisa AO, Sigbeku OF (2012) Cysts of the oro-facial region: A Nigerian experience. Journal of Oral Maxillofacial Pathology 16, 167–171.
    21. Ledesma-Montes C, Herna´ndez-Guerrero JC, Garce´s-Orti´z M (2000) Clinico-pathologic study of odontogenic cysts in a Mexican sample population. Archives of Medical Research 31,373–6.
    22. Li TJ, Kitano M, Chen XM (1998) Orthokeratinized odontogenic cyst: a clinicopathological and immunocytochemical study of 15 cases. Histopathology 32, 242–251.
    23. Luo HY, Li TJ (2009) Odontogenic tumors: A study of 1309 cases in a Chinese population. Oral Oncology 45, 706–711.
    24. Masthan KMK, Rajkumari S, Deepasree M, Babu1 NA, Sankari SL (2011) Neoplasms associated with odontogenic cysts. Journal of Dentistry and Oral Hygiene 3, 123-130.
    25. Meningaud JP, Oprean N, Pitak-Arnnop P, Bertrand JC (2006) Odontogenic cysts: A clinical study of 695 cases. Journal of Oral Science 48, 59–62.
    26. Mosqueda-Taylor A, Irigoyen-Camacho ME, Diaz-Franco MA, Torres-Tejero MA (2002) Odontogenic cysts: Analysis of 856 cases. Dental Medical clinic 7, 89–96.
    27. Nakamura T, Ishida J, Nakano Y, Ishi T, Fukumoto M, Izumi H et al (1995) A study of cysts in the oral region: Cysts of the jaws. Journal of Nihon University School of Dentistry 37, 33-40.
    28. Ochsenius G, Escobar E, Godoy L, Peñafiel C (2007) Odontogenic Cysts: Analysis of 2.944 cases in Chile. Medicina Oral Patologia Oral y Cirugia Bucal 12, 85-91.
    29. Ochsenius G, Ortega A, Godoy L, Penafiel C, Escobar E (2002) Odontogenic tumors in Chile: a study of 362 cases. Journal of Oral Pathology and Medicine 31,415–20.
    30. Odukoya O (1995) Odontogenic tumours: Analysis of 289 Nigerian cases. Journal of Oral Pathology and Medicine 25,454-7.
    31. Pechalova PF, Bakardjiev AJ (2009) Cysts of the Jaws: a Clinical Study of 621 Cases. 43, Acta stomatologica Croatica 215-224.
    32. Pereira da-Costa DO, Maurício AS, Silvestre de-Faria PA, Esmeraldo da-Silva L, Taylor AM, Chaves Lourenço SQ (2012) Odontogenic tumors: A retrospective study of four Brazilian diagnostic pathology centers. Medicina Oral Patologia Oral y Cirugia Bucal 17,389-94.
    33. Philipsen HP (2005) Keratocystic odontogenic tumor. WHO Classification of Tumors: Pathology and genetics of head and neck tumors. Lyon: IARC Press, pp. 306–7.
    34. Prockt AP, Schebela CR, Maito FDM, Filho MSA, Rados PV (2008) Odontogenic Cysts: Analysis of 680 Cases in Brazil. Head and Neck Pathology 2,150–156.
    35. Ramachandra P, Maligi P, Raghuveer HP (2011) A cumulative analysis of odontogenic cysts from major dental institutions of Bangalore city: A study of 252 cases. Journal of Oral and Maxillofacial Pathology 15, 1–5.
    36. Regezi JA, Kerr DA, Courtney RM (1978) Odontogenic tumors: analysis of 706 cases. Journal of Oral Surgery 36, 771–778.
    37. Regezi JA, Sciubba J (1993) Oral pathology Clinical-pathologic correlations. WB Saunders, Philadelphia, pp. 362-397.
    38. Sanatkhani M, Zarch HH, Pakfetrat A, Falaki F (2011) Odontogenic Cysts: a Clinical and Radiographic Study of 58 Cases. Australian Journal of Basic & Applied Sciences 5, 329-333.
    39. Sandhu SV, Narang RS, Jawanda M, Rai S (2010) Adenomatoid odontogenic tumour associated with dentigerous cyst of the maxillary antrum: A rare entity. Journal of Oral and Maxillofacial Pathology 14, 24-8.
    40. Santos JN, Pinto LP, Figueredo CRLV, Souza LB (2001) Tumores odontogenicos: analise de 127 cases. Pesquisa Odontológica Brasileira 15,308-13.
    41. Sato M, Tanaka N, Sato T, Amagasa T (1997) Oral and maxillofacial tumors in children: a review. Brazilian Journal of Oral and Maxillofacial Surgery 35, 92–95.
    42. Sharifian MJ, Khalili M (2011) Odontogenic cysts: a retrospective study of 1227 cases in an Iranian population from 1987 to 2007. Journal of Oral Science 53, 361-367.
    43. Shear M, Speight P (200) Cysts of the oral and maxillofacial regions. Oxford: Blackwell Munksgaard.
    44. Sriram G, Shetty RP (2008) Odontogenic tumors: a study of 250 cases in an Indian teaching hospital. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 105, 14–21.
    45. Tanaka N, Murata A, Yamaguchi A, Kohama G (1999) Clinical features and management of oral and maxillofacial tumors in children. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 88, 11–15.
    46. Tawfik MA, Zyada MM (2010) Odontogenic tumors in Dakahlia, Egypt: analysis of 82 cases. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 109, 67-73.
    47. Taylor MA, Montes CL, Sandoval SC, Robertson JP, Godoy Rivera LMR, Garcia AM (1997) Odontogenic tumors in Mexico: a collaborative retrospective study of 349 cases. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 84, 672–675.
    48. Varinauskas V, Gervickas A, Kavoliu-niene O (2006) Analysis of odontogenic cysts of the jaws. Medicina (Kaunas) 42, 201–7.
    49. Waldron CA (1995) Oral and maxillofacial pathology. WB Saunders, Philadelphia, pp. 493–538.
    50. Wright JM (1981) The odontogenic keratocyst: orthokeratinized variant. Oral Surgery Oral Medicine Oral Pathology Oral Radiology Endodontology 51, 609–618.
    51. Wu PC, Chan KW (1985) A survey of tumors of the jawbones in Hong Kong Chinese: 1963-82. Brazilian Journal of Oral and Maxillofacial Surgery 23, 92–102.
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  • How to Cite

    K C, N., & Shaikh, Z. (2014). Clinicopathological correlation of odontogenic cysts and tumours in a South Indian population over a 20-year period. International Journal of Dental Research, 2(2), 32-36. https://doi.org/10.14419/ijdr.v2i2.1590