Central giant cell granuloma of mandible: a case report

  • Authors

    • Dr. Jaishri Pagare Post graduate student Department of oral medicine and radiology, GDCH Chhatrapati Sambhajinagar
    • Dr. Gayatri Kale GOVERNMENT DENTAL COLLGEGE AND HOSPITAL AURANGABAD
    2024-11-07
    https://doi.org/10.14419/bbe59f70
  • Central Giant Cell Granuloma(CGCG); Giant Cell Lesion; Giant Cell Tumour; Multilocular Lesions.

  • Abstract

    Central Giant Cell Granuloma(CGCG) and giant cell tumour of jawbone are grouped underneath same umbrella but with distinct clinical behavior. CGCG is a rare benign lesion of the jaws distinguish by the presence of multinucleated giant cells within a fibrous stroma. The pathogenicity of CGCG still remains an enigma, which demands the differentiation from other look-alike lesions in order to have proper diagnosis and treatment planning.  In this article, a case of CGCG in a 30-year-old female patient who presented with complaints of gradually increasing swelling and discomfort in the mandible is described.

  • References

    1. Jaffe HL. Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-oseous) dysplasia of the jawbones. Oral Surg Oral Med Oral Pathol. 1953 Jan;6(1):159–75. https://doi.org/10.1016/0030-4220(53)90151-0.
    2. Edwards PC. Insight into the pathogenesis and nature of Central Giant Cell Lesions of the Jaws. Med Oral Patol Oral Cir Bucal. 2015 Mar 1;20(2):e196-198. https://doi.org/10.4317/medoral.20499.
    3. Balaji P, Balaji SM. Central giant cell granuloma - A case report. Indian J Dent Res. 2019;30(1):130–2. https://doi.org/10.4103/ijdr.IJDR_437_19.
    4. de Lange J, van den Akker HP, van den Berg H. Central giant cell granuloma of the jaw: a review of the literature with emphasis on therapy options. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Nov;104(5):603–15. https://doi.org/10.1016/j.tripleo.2007.04.003.
    5. Ramesh V. “Central giant cell granuloma” - An update. J Oral Maxillofac Pathol. 2020;24(3):413–5. https://doi.org/10.4103/jomfp.jomfp_487_20.
    6. Antoine ButelAntoine Butel AB Gemma Di Bernardo and Beatrice Louvet. Central giant cell granuloma: a case report. J Oral Med Oral Surg. 2017 Oct 19; https://doi.org/10.1051/mbcb/2017024.
    7. Chuong R, Kaban LB, Kozakewich H, Perez-Atayde A. Central giant cell lesions of the jaws: a clinicopathologic study. J Oral Maxillo-fac Surg. 1986 Sep;44(9):708–13. https://doi.org/10.1016/0278-2391(86)90040-6.
    8. Tahmasbi-Arashlow M, Patel PB, Nair MK, Liang H, Cheng YSL. Cone-beam computed tomographic imaging of central giant cell gran-uloma: A comprehensive review. Imaging Sci Dent. 2022 Jun;52(2):123–31. https://doi.org/10.5624/isd.20220130.
    9. Omami G. Multilocular Radiolucency of the Mandibular Ramus and Body. Ear Nose Throat J. 2022 Jun;101(5):292–3. https://doi.org/10.1177/0145561320955130.
    10. Akinyamoju AO, Soyele OO, Saiki TE, Adesina OM. Giant Cell Lesions of the Jaws:A Review and Comparative Histopathological Study. West Afr J Med. 2020;37(1):26–31.
    11. Jeyaraj P. Management of Central Giant Cell Granulomas of the Jaws: An Unusual Case Report with Critical Appraisal of Existing Liter-ature. Ann Maxillofac Surg. 2019;9(1):37–47. https://doi.org/10.4103/ams.ams_232_18.

  • Downloads

  • How to Cite

    Jaishri Pagare , D., & Gayatri Kale , D. (2024). Central giant cell granuloma of mandible: a case report. International Journal of Dental Research, 10(2), 20-23. https://doi.org/10.14419/bbe59f70