Central giant cell granuloma of the maxilla: a case re-port

  • Authors

    • Najwa Alchalabi
    • Hayder Salih
    • Ahmed Merza alkarkh general hospital
  • Maxillary Central Giant Cell Granuloma, CGCG, Facial Degloving Approach
  • Introduction: Central giant-cell is a benign lesion that predominantly involves the bone of the mandible and maxilla with a wide variation of its behavior. Surgery usually is the first choice in treatment of central giant cell granuloma.

    Case Report: In this case report we present a 29 years-old female with well define swelling on left maxilla. Diagnosis through incisional biopsy showed a central giant cell granuloma. Surgery with curettage was our treatment option with a follow up( 2 years ), No recurrence was reported.

    Discussion: Information on the maxillary central giant cell granuloma in published studies is insufficient. So here we present our case as unusual case presentation. Differential diagnosis of this case included osteosarcoma (parosteal type) since the tumor clinical presentation in periosteous tissue adjacent to the bone cortex and showed rapid growth. We chose the conventional surgical treatment by simple surgical curettage by mid-face degloving approach to avoid any facial scaring.

  • References

    1. [1] Manish Gupta, Monica Gupta,Sunder Singh, and RupinderKaur. Central giant cell granuloma of the maxilla: BMJ Case Rep. 2013; 2013: bcr2013009102. Published online 2013 Mar 7. https://doi.org/10.1136/bcr-2013-009102.

      [2] C. Padmavathi Devi, T. Swaroopkanth, G. Sudhakar, D. Kiranmai, R. Sasank, and D. Sridharreddy. Central giant cell granuloma of maxilla: a case report Indian J Otolaryngol Head Neck Surg. 2013 Jul; 65(Suppl 1): 192–194. Published online 2012 Mar 21. https://doi.org/10.1007/s12070-012-0538-1.

      [3] Anthony M Pogrel. The diagnosis and management of giant cell lesions of the jaws: annals of maxillofacial surgery Year : 2012 | Volume : 2 | Issue : 2 | Page : 102-106.

      [4] Isidoro Rubio-Correa, DamiánManzano-Solo de Zaldívar, Raúl González-García, LuísRuíz-Laza, Laura Villanueva-Alcojol, David González-Ballester, Cristina Hernández Vila, and Florencio Monje-Gil. Giant cell granuloma of the maxilla. Global management, review of literature and case report: J ClinExp Dent. 2012 Apr; 4(2): e129–e131.Published online 2012 Apr 1. https://doi.org/10.4317/jced.50701.

      [5] Plontke S K, Adler C P, Gawlowski J, Ernemann U, Friese S A, Plinkert P K. Recurrent giant cell reparative granuloma of the skull base and the paranasal sinuses presenting with acute one-sided blindness. Skull Base. 2002; 12:9–17 https://doi.org/10.1055/s-2002-21568-1.

      [6] Yu J L, Qu L M, Wang J, Huang H Y. Giant cell reparative granuloma in the temporal bone of the skull base: report of two cases. Skull Base. 2010; 20:443–448. https://doi.org/10.1055/s-0030-1265822.

      [7] Comert E, Turanli M, Ulu S. Oral and intralesional steroid therapy in giant cell granuloma. ActaOtolaryngol. 2006; 126:664–6 https://doi.org/10.1080/00016480500468976.

      [8] Goldman KE, Marshall MK, Alessandrini E, Bernstein ML. Complications of alpha-interferon therapy for aggressive central giant cell lesion of the maxilla. Oral Surg Oral Med Oral Pathol Oral RadiolEndod. 2005; 100:285–91. https://doi.org/10.1016/j.tripleo.2004.11.024.

      [9] TelfahH, and Abdel Latif. Oral granulomas at prince rashid hospital North Jordan. A retrospective study of 62 cases JRMS. 2006; 13:41–45.

      [10] AmiralaAghbali, MahmoodSina, Seyyed Mahdi VahidPakdel, ParyaEmamverdizadeh, Maryam Kouhsoltani, SeyyedMostafaMahmoudi, and Maryam Janani. Correlation of Histopathologic Features with Demographic, Gross and Radiographic Findings in Giant Cell Granulomas of the Jaws: J Dent Res Dent Clin Dent Prospects. 2013 autumn; 7(4): 225–229.Published online 2013 Dec 18.

      [11] Amirchaghmaghi M, Falaki F, Mohtasham N, and Imanimoghaddam M. Amirchaghmaghi M, Falaki F, Mohtasham N, and ImanimoghaddamMCentral. Giant cell granuloma of the jaws: a clinical and radiographic study in Khorasan (Iran) J. Applied Sci. 2010; 10:777–780. https://doi.org/10.3923/jas.2010.777.780.

      [12] Bataineh AB, Al-Khateeb T, Rawashdeh MA. The surgical treatment of central giant cell granuloma of the mandible. J Oral Maxillofac Surg. 2002; 60:756–61. https://doi.org/10.1053/joms.2002.33241.

      [13] Nogueira RLM, Teixeira RC, Cavalcante RB, Ribeiro RA, Rabenhosrt SHB. Intralesional injection of triamcinolone hexacetonide as na alternative treatment for central giant-cell granuloma in 21 cases. Int J Oral Maxillofac Surg. 2010; 39 (Suppl 12):1204–1210 https://doi.org/10.1016/j.ijom.2010.06.015.

      [14] Newton Guerreiro da Silva, Júnior,1 AlineSemblano Dias Carreira,1,4 Erick Nelo Pedreira,2 FabrícioMesquita Tuji,1Karem López Ortega,3 and João de Jesus Viana Pinheiro2 .Treatment of central giant cell lesions using bisphosphonates with intralesional corticosteroid injections. Head Face Med. 2012; 8: 23. Published online 2012 Aug 22. https://doi.org/10.1186/1746-160X-8-23.

      [15] M. A. Rawashdeh, A. B. Bataineh, T. Al-Khateeb: Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla. International Journal of Oral and Maxillofacial Surgery, Vol. 35, Issue 1, p60–66 Published in issue: January 2006

      [16] R.L.M. Nogueira, R.C. Teixeira, R.B. Cavalcante, R.A. Ribeiro, S.H.B. RabenhosrtIntralesional injection of triamcinolone hexacetonide as an alternative treatment for central giant-cell granuloma in 21 cases International Journal of Oral and Maxillofacial Surgery, Vol. 39, Issue 12, p1204–1210 Published online: August 2, 2010.

      [17] E. Mujica, H. Rivera, R. Rodriguez, M.J. Fernandez, C. Guerrero Midfacedegloving approach for tumors removal. International Journal of Oral and Maxillofacial Surgery, Vol. 40, Issue 10, p1183–1184 Published in issue: October 2011.

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  • How to Cite

    Alchalabi, N., Salih, H., & Merza, A. (2017). Central giant cell granuloma of the maxilla: a case re-port. International Journal of Dental Research, 5(2), 145-147. https://doi.org/10.14419/ijdr.v5i2.8095