Concentrations and health risks assessment of heavy metals in cigarettes within Baghdad city

 
 
 
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  • Abstract


    The risks associated with smoking can be due to the inhalation of toxic substances like heavy metals and polycyclic aromatic hydrocarbons (PAHs) that can be released during tobacco burns. In the present study we measured lead Pb and three other metals (cadmium Cd; Chrome Cr; and Zinc Zn) by flame atomic absorption spectroscopy (FAAS). In a twenty-five brands of cigarettes, assessing potential related health risks estimated intakes of these metals. The Related Cancer Risk (RCR) and Average Daily Intake (ADI) were calculated. The results revealed that the average values of Pb, Cd, Cr and Zn concentrations were (4.56, 0.39, 3.31 and 1.36) μg/g respectively. The total value of these four metals is greater than the range of cancer risk specified by USEPA.

     

     


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  • References


      [1] World Health Organization 2013 Tobacco fact sheet No 339. Updated July 2013. Available at: http://www. who.int/mediacentre/factsheets/fs339/en/ (Accessed: 18 November 2013).

      [2] Smitha CJ, Perfettia TA, Gargb R, Hanschb C 2003 IARC carcinogens reported in cigarette mainstream smoke and their calculated log P values. Food and Chemical Toxicology 41, 807–817. https://doi.org/10.1016/S0278-6915(03)00021-8.

      [3] Viana GF, Garcia KS, Menezes-Filho JA 2011 Assessment of carcinogenic heavy metals in Brazilian cigarettes. Environ Monit Assess 181, 255–265. https://doi.org/10.1007/s10661-010-1827-3.

      [4] Caruso RV, O’Connor RJ, Stephens WE 2013 Toxic Metal Concentrations in Cigarettes Obtained from the U.S. Smokers in 2009: Results from the International Control (ITC) United States Survey Cohort. Int J Environ Res Public Health: 10. https://doi.org/10.3390/ijerph110100202.

      [5] Omari MO, Kibet JK, Cherutoi JK, Bosire JO, Rono NK 2015 Heavy Metal Content in Mainstream Cigarette Smoke of Common Cigarettes Sold in Kenya, and their Toxicological Consequences, International Research Journal of Environment Sciences. 4(6), 75-79.

      [6] Stojanović, D, Nikić, D, Lazarević K 2004 The level of nickel in smoker's blood and urine. Cent. Eur.J. Public Health. 12, 187–189.

      [7] Galazyn SM, Brzóska MM, Moniuszko JJ 2008 Estimation of Polish cigarettes contamination with cadmium and lead, and exposure to these metals via smoking. Environ. Monit.Assess. 137, 481–493. https://doi.org/10.1007/s10661-007-9783-2.

      [8] Richter PA, Bishop EE, Wang J, Swahn MH 2009 Tobacco smoke exposure and levels ofurinary metals in the U.S. youth and adult population: the National Health and Nutrition Examination Survey (NHANES) 1999–2004. Int. J. Environ. Res. Public Health. 6, 1930–1946. https://doi.org/10.1007/s10661-007-9783-2.

      [9] Tellez PM, Navas AA, Caldwell KL, Menke A, Muntner P, Guallar E 2012 Reduction in cadmium exposure in the United States population, 1988–2008: The contribution of declining smoking rates. Environ. Health Perspect 120, 204–209. https://doi.org/10.1289/ehp.1104020.

      [10] Agency for toxic substances and disease registry (ATSDR) 2012 Toxicological Profile for Cadmium, U.S. Department 433 of Health and Human Services, Public Health Service. https://www.atsdr.cdc.gov/toxprofiles/tp.asp?id=48&tid=15.

      [11] Elinder CG, Kjellstrom T, Lind B Linnman I, Piscator M, Sundstedt K 1983 Cadmium exposure from smoking cigarette, variations with times and country where purchased, Environ Res. 32(1): 220-227. https://doi.org/10.1016/0013-9351(83)90209-8.

      [12] Hossain TM, Hassi U, Imamu SM 2018 Assessment of concentration and toxicological (Cancer) risk of lead, cadmium and chromium in tobacco products commonly available in Bangladesh, Toxicology Reports, 5: Pages 897-902. https://doi.org/10.1016/j.toxrep.2018.08.019.

      [13] Ashraf MW 2012 Levels of HeavyMetals in Popular Cigarette Brands and Exposure to TheseMetals via Smoking, the Scientific World Journal, Volume, Article ID 729430, 5. https://doi.org/10.1100/2012/729430.

      [14] Ziarati P, Mousavi Z, Pashapour S 2017 Analysis of Heavy Metals in Cigarette Tobacco, Journal of Medical Discovery. 2(1): jmd16006; https://doi.org/10.24262/jmd.2.1.16006.

      [15] Chiba, Momoko & Masironi, Roberto 1992 Toxic and trace elements in tobacco and tobacco smoke / M. Chiba & R. Masironi. Bulletin of the World Health Organization 1992; 70(‎2)‎ : 269-275. https://apps.who.int/iris/handle/10665/49331.

      [16] Caruso RV, Richard J. O’Connor W, Edryd Stephens E, Cummings M, Geoffrey TF 2014 Toxic Metal Concentrations in Cigarettes Obtained from U.S. Smokers in 2009: Results from the International Tobacco Control (ITC) United States Survey Cohort, International Journal of Environmental Research and Public Health, 11, 202-217. https://doi.org/10.3390/ijerph110100202.

      [17] California Environmental Protection Agency (CEPA) 2009 Technical Support Document for Cancer potency Factors: Methodologies for Derivation, Listing of Available Values and Adjustments to Allow for Early Life Stage Exposures: Appendix- a. https://oehha.ca.gov/media/downloads/crnr/tsdcancerpotency.pdf.

      [18] Fowles J and Dybing E 2003 Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke, Tob. Control 12 (4) (2003) 424–430. https://doi.org/10.1136/tc.12.4.424.

      [19] Pankow JF, Watanabe KH, P.L. Toccalino PL, et al. 2007 Calculated cancer risks for conventional and “potentially reduced exposure product” cigarettes, Cancer Epidemiol. Biomarkers Prev. 16 (3) 584–592. https://doi.org/10.1158/1055-9965.EPI-06-0762.

      [20] Haleem AM, Amin SA, Mahmood UH 2020 Heavy metal and polycyclic aromatic hydrocarbons in cigarettes: An analytical assessment. Popul. Med. 2020;2(June):19. https://doi.org/10.18332/popmed/122558.

      [21] Sarah CW, Prieto-Merino D, Edwards P, Cleland J, Stevens G, Roberts I. (2012). The weight of nations: an estimation of adult human biomass, BMC Public Health. 12: 439. https://doi.org/10.1186/1471-2458-12-439.

      [22] World Health Organization (WHO) 2009 Global Adult Tobacco Survey: Bangladesh Report, Country Office for Bangladesh Ministry of Health and Family Welfare, Government of the People's Republic of Bangladesh. http://www.searo.who.int/bangladesh/publications/gats_2009/en/.

      [23] United States Environmental Protection Agency (USEPA) 1989 Washington, D.C (1989), 20450, Risk Assessment Guidance for Superfund Volume I Human Health Evaluation Manual: Part A. https://www.epa.gov/sites/production/files/2015-09/documents/rags_a.pdF.


 

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Article ID: 31470
 
DOI: 10.14419/ijpr.v9i1.31470




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