The immunibiochemical effect of synobiotic and phytobiotic in vaccinated and unvaccinated chicken

  • Authors

    • marwa Kamel O. I. VETERINARY MEDICINE
    • Ashraf A. A. El-Komy
    • Enas A. A. Farag
    2021-05-22
    https://doi.org/10.14419/ijpt.v9i1.31537
  • Synobiotic, Phytobiotic, Vaccinated, Unvaccinated, Chicken.

  • Abstract

    The current study was conducted to evaluate the effects of dietary supplementation of synbiotics, phytobiotics and their mixture on some blood parameters with respct to kidney and liver functions and some histological criteria of broilers. A total of 200 broiler chicks were randomly chosen and divided into eight groups (25 bird in each). The first four groups were unvaccinated chicken and allotted to four dietary treatments, either fed a basal diet (group 1) or the same diet supplemented with 1g synbiotic /kg body weight ( group 2) , 1g phytobiotic /kg body weight (group 3) and 1g synbiotic plus 1g phytobiotic/kg body weight (group 4) .The same previous treatments were received by four vaccinated chicken groups 5, 6,7 and 8 , respectively. Synobotic and phytobiotic tended to increase AST and ALT levels in vaccinated chicken during different periods. The mixture synbiotic and phytobiotic led to no significant increase in AST with unvac-cinated and increase of ALT level in vaccinated groups. Also, previous feed additive increased total protein in both vaccinated and unvac-cinated chickens. Supplementation mixture of both synbiotic and phytobiotic to diet increased total protein in unvaccinated and vaccinated chicken. Rations supplemented with synobiotic and phytobiotic increased albumin level in unvaccinated chicken and decreased with vac-cinated chicken during different periods. Consequently, mixtures of synobiotic and phytobiotic appeared the same trend. On the other, using synobiotic and phytobiotic showed increase globulin level with unvaccinated chicken and decrease with vaccinated chicken, while the mixture of them gave higher level of globulin with unvaccinated or vaccinated chicken during different periods, except at 21 day, the globulin level had slight decrease with unvaccinated chicken. At the same time supplementation synobiotic and phytobiotic or their mixture with unvaccinated or vaccinated chicken revealed normal histological criteria. In conclusion, dietary supplementation of syonbiotic and phytobiotic improved the gut health by decreasing the caecal total coliform count with no adverse effect.
    The aim of this experiment is to study the effect of dietary supplementation of synobiotic, phytobiotic and their mixture on kidney and liver functions and some histological criteria of broiler chicken.



  • References

    1. [1] Amad, A.A.; Männer, K.; Wendler, K.R.; Neumann, K. and Zentek, J. (2011). Effects of a phytogenic feed additive on growth performance and ileal nutrient digestibility in broiler chickens. Poultry Science, 90: 2811–281. https://doi.org/10.3382/ps.2011-01515.
      [2] Abdelrafea A. E.; Mohammed A. A.; Abdelrahman A.S. and Arafa, M.M. (2013): Influence of Different Levels of Astragalus Root Powder in Broiler Chick Diets on the Physiological and Biochemical Changes. Journal of Applied Sciences Research, 9(3): 2104-2118, 2013 ISSN 1819-544X.
      64 International Journal of Pharmacology and Toxicology
      [3] Akbarian, A.; Golian, A.; Kermanshahi, H.; Gilani, A. and Moradi, S. (2012): Influence of turmeric rhizome and black pepper on blood constituents and performance of broiler chickens. African Journal of Biotechnology, 11(34): 8606-8611. https://doi.org/10.5897/AJB11.3318.
      [4] Alaeldein M. A.; Mohamed A.M. (2015): Effects of the Dietary Inclusion of a Probiotic, a Prebiotic or their Combinations on the Growth Performance of Broiler Chickens. Brazilian Journal of Poultry Science. . vol.17 .099-104.
      [5] Ashayerizadeh A.; Dabiri N.; Mirzadeh K. H. M. and Ghorbani M. R. (2011): Paper Effect of dietary supplementation of probiotic and prebiotic on growth indices and serum biochemical parameters of broiler chickens. Journal of Cell and Animal Biology Vol. 5(8), pp. 152-156
      [6] Bancroft, J.D.and Gamble, M. (2008):“Theory and Practice of Histological Techniques.’’ 6th ED., Churchill Livingstone, Elsevier, China. 2008.
      [7] Doumas, B. T. (1975): Colorimetric determination of total proteins.Clin. chem.21,1159.1166. https://doi.org/10.1093/clinchem/21.8.1159.
      [8] Duncan, D.B. (1955): Multiple range and multiple F tests. Biometrics 11: 1–42. https://doi.org/10.2307/3001478.
      [9] Erdogan, Z.; Erdogan, S.; Aslantas,O. and Celik,S. (2010) : Effects of dietary supplementation of synbiotics and phytobiotics on performance, caecal coliform population and some oxidant/antioxidant parameters of broilers .Journal of Animal Physiology and Animal Nutrition. https://doi.org/10.1111/j.1439-0396.2009.00973.x.
      [10] Folin, O. Z.(1934): Colorimetric determination of creatinine Phys.Chem.268:228. https://doi.org/10.1515/bchm2.1934.228.3-6.268.
      [11] Heidland A.; Horl W.H.; Schaefer R.M.; Teschner M.; Weipert J.and Heidbreder E. (1985): Role of alcohol in clinical nephrology.. Klin Wochenschr ;63:948. https://doi.org/10.1007/BF01738150.
      [12] Jagmohan Singh.; K. M. Koley.; Khushboo Chandrakar. and Nileshkumar S. Pagrut. (2013): Effects of Aloe vera on dressing percentage and haemato-biochemidal parameters of broiler chickens. Veterinary World, EISSN: 2231-0916. https://doi.org/10.14202/vetworld.2013.803-806.
      [13] Murarolli V.I; Burbarelli M.; Polycarpo G.I; Ribeiro P.; Moro M.AND Albuquerque R. (2014): Prebiotic, probiotic and symbiotic as alternative to ntibiotics on the Performance and Immune Response of Broiler Chickens. Brazilian Journal of Poultry Science. . vol.16 no.3.
      https://doi.org/10.1590/1516-635x1603279-284.
      [14] Reitmans, S. and Frankel, S. (1957): Reitman-Frankel colourimetric method of Got/ As T and GPT/ALT Tromsaminales. Am. J. Clin. Path. 28: 56-63. https://doi.org/10.1093/ajcp/28.1.56.
      [15] Sawsan M. E.; Abdalim F. A.; Mohamed K. M.; Mohamed S. H. E and (2019) Science. Volume 10 (3): 134-140, 2016.
      [16] Sobayo R.A., Adeyemi O.A., Oso A.O., Fafiolu A.O., Daramola J.O., Sodipe G., I Ogunade IB, Odetolao O.M.(2013): Haematological, serum and carcass characteristics of broiler chicken fed `graded levels of Garcinia kola (Bitter kola) used as phytobiotic. Nigerian Journal of Animal Production. Vol 40, No 1. https://doi.org/10.51791/njap.v40i1.623.
      [17] Satyapal S.U.; Kadam V.J.and Ghosh R. (2008): Hepatoprotective activity of Livobond, a polyherbal formulation against CCl4 induced hepatotoxi-city in rats. Int J Pharm; 4:472-6. https://doi.org/10.3923/ijp.2008.472.476.
      [18] Sawsan M. E.; Abdalim F. A.; Mohamed K. M.; Mohamed S. H. E and Science. Volume 10 (3): 134-140, 2016.
      [19] Sanja J. P.; Ljiljana M. K., Nikola M. P., Jovanka D. L., Olivera M. Ä.; Bojana M. K.; Ivana S. ÄŒ.and Marina V. V. (2015): Effect of synbiotic on growth and antioxidant status of blood in broiler chicken Journal of the Institute of Food Technology in Novi Sad. Volume 42, Issue 2.163-169
      [20] Tietz N.W. (2000): Fundamentals of clinical chemistry. 6 thed Philadephia, PA: Saunders. p. 744-5, 788-9.
      [21] White, B. A.; Erickson, M. M.; and Stevens, S.G. (1970): Colorimetric determination of uric acid. Chemistry for medical technologists 3rd ed C. V. Mosby Company, saint Louis,U.

  • Downloads

  • How to Cite

    Kamel O. I., marwa, A. A. El-Komy, A., & A. A. Farag, E. (2021). The immunibiochemical effect of synobiotic and phytobiotic in vaccinated and unvaccinated chicken. International Journal of Pharmacology and Toxicology, 9(1), 56-64. https://doi.org/10.14419/ijpt.v9i1.31537

    Received date: 2021-04-12

    Accepted date: 2021-05-08

    Published date: 2021-05-22