Pharmacological effect of synobiotic and phytobiotic in kidney function and some blood parameters of chicken

 
 
 
  • Abstract
  • Keywords
  • References
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  • Abstract


    The aim of this research was to study the effects of dietary supplementation of ‎synbiotic, phytobiotics and their mixture on kidney functions, some blood parameters and histological criteria of broilers. A total of 200 ‎broiler chicks were randomly chosen and divided into eight groups (25 birds in each). The first four groups were unvaccinated chicken which received a basal diet (group 1) or ‎the same diet supplemented with 1g synobiotic /kg body weight (group 2), 1g phytobiotic /kg body weight (group 3) and 1g ‎synobiotic plus 1g phytobiotic/kg body weight (group 4). The second four groups were vaccinated chicken and fed the same previous treatments with groups 5, 6, 7 and 8, respectively. Therapeutic dose of synobiotic and phytobiotic or their mixture (1ml/ kg. body weight) orally for 3 ‎successive days ‎tended to decrease uric acid and creatinine in unvaccinated and vaccinated chicken at 7, 14 and 21 day. In this study uric acid and ‎creatinine levels resulted in decrease, showing a significant improvement of kidney functions‎ ‎. Some different parameters of blood and histological criteria showed normal measurements with no adverse effect of treatments.

     

     

     

  • Keywords


    Synobiotic; Phytobiotic; Vaccinated; Unvaccinated; Chicken.

  • References


      [1] Alaeldein M. A.; Mohamed A.M.(2015): Effects of the Dietary Inclusion of ‎a Probiotic, a Prebiotic or their ‎Combinations on the Growth Performance ‎of Broiler Chickens. Brazilian Journal of Poultry Science.‎‏ ‏‎. vol.17 ‎‏.‏‎099-104‎‏.‏

      [2] Abdelrafea A. E.; Mohammed A. A.; Abdelrahman A.S. and ‎Arafa, ‎M.M. ‎‎(2013): Influence of Different Levels of Astragalus Root ‎Powder in ‎Broiler Chick ‎Diets on the Physiological and Biochemical Changes. ‎Journal of ‎Applied Sciences ‎Research, 9(3): 2104-2118, 2013 ISSN 1819-‎‎544X.‎

      [3] Amad, A.A.; Männer, K.; Wendler, K.R.; Neumann, K. ‎and ‎Zentek, ‎J. ‎‎(2011). Effects of a phytogenic feed additive on ‎growth ‎performance ‎and ‎ileal nutrient digestibility in broiler chickens. ‎Poultry ‎Science, 90: ‎‎2811–‎‎281.‎ https://doi.org/10.3382/ps.2011-01515.

      [4] Ashayerizadeh‎ A.; Dabiri N.; Mirzadeh‎ K. H. M. and Ghorbani‎ M. R. ‎‎(2011): ‎ Paper Effect of dietary supplementation of probiotic and ‎prebiotic on ‎growth indices and serum biochemical parameters of broiler ‎chickens. Journal of Cell and Animal Biology Vol. 5(8), pp. 152-156‎.

      [5] Awad K. Ghareeb S. Abdel-Raheem J. Böhm (2008): Effects of dietary ‎inclusion of probiotic and synbiotic on growth ‎performance, organ ‎weights, ‎and intestinal histomorphology of broiler ‎chickens. Poultry ‎Science, Volume ‎(7): 686-691‎.‎

      [6] ‎ Bancroft, J.D.and Gamble, M. (2008) :“Theory and Practice of ‎Histological Techniques.’’ ‎‎6th ED., Churchill Livingstone, Elsevier, ‎China. 2008.‎‎

      [7] Beski S.S.M and Al-Sardary‎‏ ‏S.Y.T(2015): effects of dietary ‎supplementation of probiotic and synbiotic on broiler chickens hematology ‎and intestinal integrity. International Journal of Poultry Science 14 (1): 31-‎‎36. https://doi.org/10.3923/ijps.2015.31.36.

      [8] Coshen,R.R.(1967):Anticoagulation, centrifugation time and sample replicate number in micro haematocrite method for avian blood https://doi.org/10.3382/ps.0460214.

      [9] Duncan, D.B. (1955): Multiple range and multiple F tests. Biometrics 11: ‎‎1–42.‎ https://doi.org/10.2307/3001478.

      [10] Erdogan, Z.; Erdogan, S.; Aslantas,O. and Celik,S. (2010) : ‎Effects ‎of ‎dietary supplementation of synbiotics and phytobiotics ‎on ‎performance, ‎caecal coliform population and some ‎oxidant/antioxidant. https://doi.org/10.1111/j.1439-0396.2009.00973.x.

      [11] Fasanmi, O.G.; Akanbi, I.O.; Adekunle, I.F.; Oladele-Bukola, ‎M.O.; ‎Makinde, G.E.O.and Fagbohun,F.A. (2014) : Comparing the ‎Phytobiotic ‎effects of feed-grade and liquid Oregostim® on ‎Performance ‎characteristics, Haematology and Serum biochemistry of ‎Finisher ‎broilers . Scholars Journal of Agriculture and Veterinary Sciences ‎‎2014; ‎‎1(3):137-142.‎

      [12] Folin, O. Z.(1934): Colorimetric determination of creatinine ‎Phys.Chem.268:228.‎ https://doi.org/10.1515/bchm2.1934.228.3-6.268.

      [13] Harison, G. J. and Harrison, L.R.(1986): Cited in clinical Avian Medicine and surgery.W.B.Saunders Company. Philadelphia, London, 58: 193-201.

      [14] Heidland , A.; Horl, W.H.; Schaefer, R.M.; Teschner, M.; Weipert, J.and Heidbreder, E.(1985): Role of alcohol in clinical nephrology. Klinische Wochenschrift, 63(18):948-958. https://doi.org/10.1007/BF01738150.

      [15] Jagmohan Singh.; K. M. Koley.; Khushboo Chandrakar. and ‎Nileshkumar ‎S. Pagrut. (2013) : Effects of Aloe vera on dressing ‎percentage and ‎haemato-biochemidal parameters of broiler chickens . ‎Veterinary World, ‎EISSN: 2231-0916 . ‎https://doi.org/10.14202/vetworld.2013.803-806.

      [16] Murarolli V.I; Burbarelli M.; Polycarpo G.I; Ribeiro P.; ‎Moro M.AND ‎Albuquerque R.(2014): Prebiotic, probiotic and symbiotic as alternative ‎to ‎ntibiotics ‎on the Performance and Immune Response of Broiler Chickens. ‎Brazilian Journal of Poultry Science.‎‏ ‏‎. vol.16 no.3‎‏.‏ ‎https://doi.org/10.1590/1516-635x1603279-284.

      [17] Mehr, M.A.; Hassanabadi, A.; Moghaddam, H.N. and ‎Kermanshahi, H. (2014): Supplementation of Clove Essential Oils and‏ ‏Probiotic to the Broiler’s Diet on Performance, Carcass Traits and Blood‏ ‏Components. Iranian Journal of Applied Animal Science, 4(1): (117-‎‎122).‎

      [18] Miraghaee, S.S.; Heidary, B.; Almasi, H.; shabani, A ; Elahi, ‎M. and Nia, M.H. (2011): The effects of Nigella sativa powder (black ‎seed) and Echinacea purpurea (L.) Moench extract on performance, ‎some blood biochemical and hematological parameters in broiler ‎chickens. African Journal of Biotechnology, 10(82): 19249-19254.‎ https://doi.org/10.5897/AJB11.2891.

      [19] Natt, M.P. and Herrick, C.A. (1952): New blood diluents for counting erythrocytes and leucocytes of chickens. Poultry Science Journal, 31:735-738. https://doi.org/10.3382/ps.0310735.

      [20] Sawsan M. E.;‎ Abdalim F. A.;‎ Mohamed K. M.; Mohamed S. H. E ‎and (2019) Science .Volume 10 (3): 134-140, 2016‎‏.‏

      [21] Sanja J. P.; Ljiljana M. K., Nikola M. P.;, ‎Jovanka D. L., Olivera M. Đ.; Bojana M. K.; Ivana S. ‎Č.and Marina V. V.(2015): Effect of synbiotic on growth and antioxidant ‎status of blood in broiler chicken Journal of the Institute of Food Technology in Novi Sad. Volume 42, Issue 2‎.‎163-169‎

      [22] SPSS Inc. Released (2009), PASW Statistics for Windows, Version 18.0. Chicago: SPSS Inc.

      [23] Sobayo R.A. , Adeyemi O.A. , Oso A.O., Fafiolu A.O., Daramola J.O., ‎Sodipe G., I Ogunade ‎ IB , Odetolao O.M.(2013): Haematological, serum and carcass characteristics of broiler chicken ‎fed `graded levels of Garcinia kola (Bitter kola) used as phytobiotic. Nigerian J. of Animal Production. Vol 40, No 1 https://doi.org/10.51791/njap.v40i1.623.

      [24] Syed M.; H.; G., Sitwat Z., Faiz ul-Ha., ‎Saddia G.and Asma A.(2018): Effect of natural growth promoters on immunity, and ‎biochemical and haematological parameters of broiler chickens. Tropical Journal of Pharmaceutical Research. ‎> vol 17, no 4 ‎.‎627-633 https://doi.org/10.4314/tjpr.v17i4.9.

      [25] White, B. A.; Erickson, M. M.; and Stevens, S.G.(1970): Colorimetric ‎determination of uric acid. Chemistry for medical technologists ‎‎3rd ed C. V. Mosby Company, saint Louis,U

      [26] Wintrobe, M.M. (1967): Colorimeterically Method for Determination Haemoglobin. Medicine Journal 12(5): 287-309.


 

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Article ID: 31574
 
DOI: 10.14419/ijpt.v9i1.31574




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