Evaluation of metals content among different cosmetic products in the Arabian market

  • Authors

    • Sahar Younes Ibrahim Md DR. SAHAR YOUNES IBRAHIM ISSA LECTURER FORENSIC MEDICINE & CLINICAL TOXICOLOGY-FACULTY OF MEDICINE-ALEXANDRIA UNIVERSITY Mobile Phone: +966550748326
    • Rania Abdel Maguid Md
    • Maha Khaled Al-Mazroua
    2016-04-13
    https://doi.org/10.14419/ijpt.v4i1.5942
  • Cosmetics, Henna, Lipstick, Heavy Metals, Aluminum, Lead, ICP-MS, Traditional Herbs, Allergic Dermatitis, Poisoning, Toxicity, Arabian Market.

  • Abstract

    Background: Cosmetics' use is very popular all over the world and in some parts of Arabian countries. The use of some cosmetics as Kohl is part of culture and traditions, and is used since very young ages. This makes detection of heavy metal content in cosmetics marketed in Egypt and other Arabian markets of crucial importance.

    Objective: To evaluate the levels of heavy metals content among different cosmetic products in the Arabian market.

    Methods: Different brands of; anti-freckle creams, eye shadows, eyeliners, facial powders, foundation, henna and lipsticks were purchased from open markets in Egypt and Saudi Arabia. Sample preparation and analysis was conducted, to estimate levels of twelve different metals (Pb, As, Cd, Ag, Ba, Al, Cr, Mn, Co, Ni, Cu, and Zn) using Inductively Coupled Plasma Mass Spectrometry (ICP-MS).

    Results: The mean concentration of some studied metals as Aluminium, lead, arsenic, copper and nickel were higher than permissible levels for cosmetics in some of the studied samples. Para- Phenylenediamine (PPD) was detected in all the studied 7 Henna samples.

    Conclusion: In conclusion, cosmetic contamination with metals above permissible levels is very common in most of the products available in the developing world and Arabian markets. Physicians and users must be aware of the probable toxicity of these elements and of the clinical signs of systemic poisoning. Considering popular use of cosmetics by different age groups, the hazardous cumulative effects of prolonged exposure to low concentrations of metals like; Aluminium, lead, Arsenic, nickel and copper especially in children, cannot be ruled out. Further studies are recommended in addition, cosmetic market control and legislation procedures should be thoroughly implemented.

  • References

    1. [1] Adal A, Tarabar A. (2013): Heavy Metal Toxicity, http://emedicine.medscape.com/article/814960-overview.

      [2] Adepoju-Bello AA, Oguntibeju OO, Adebisi RA, Okpala N, Coker HAB. (2012): Evaluation of the concentration of toxic metals in cosmetic products in Nigeria. Afr J Biotechnol; 11:16360 – 4.

      [3] Ahmed S, Rahman A, Alam A, Saleem M, Athar M, Sultana S (2000):Evaluation of the efficacy of Lawsonia alba in the alleviation of carbon tetrachloride-induced oxidative stress. J. Ethnopharmacol. 69: 157 – 64. http://dx.doi.org/10.1016/S0378-8741(99)00091-4.

      [4] Al-Dayel O, Hefne J, Al-Ajyan T. (2011): Human exposure to heavy metals from cosmetics. Orient. J. Chem. 27 (1), 01–11.

      [5] Al-Saleh I, Al-Enazi S, Shinwari N. (2009): Assessment of lead in cosmetic products. Regul Toxicol Pharmacol; 54:105–13. http://dx.doi.org/10.1016/j.yrtph.2009.02.005.

      [6] Al-Trabulsy, HAM, Khater AEM, Habani, FI. (2013): Heavy elements concentrations, physicochemical characteristics and natural radionuclides levels along the Saudi coastline of the Gulf of Aqaba. Arab. J. Chem. 6, 183– 9. http://dx.doi.org/10.1016/j.arabjc.2010.10.001.

      [7] Amparo Salvador and, Alberto Chisvert (2007): General Concepts and Cosmetic Legislation, In: Analysis of cosmetic products. Elsevier; Kidlington, Oxford; 1 - 42.

      [8] Amartey, E.O., Asumadu-Sakvi, A.B., Adjei, C.A., et al. (2011): Determination of heavy metals concentration in hair pomades on the Ghanian market using atomic absorption spectrometry technique. Br. J. Pharmacol. Toxicol. 2 (4), 192–8.

      [9] ATSDR: Agency for Toxic Substances and Disease Registry, (2012): Public Health Statement for Cadmium: September 2012. Available at http://www.atsdr.cdc.gov. Accessed on 10.04.2013.

      [10] Ayenimo JG, Yusuf AM, Adekule AS, Makinde OW (2010): Heavy metal exposure from personal care product. Bull. Environ. Contam. Toxicol. 84, 8–14. http://dx.doi.org/10.1007/s00128-009-9867-5.

      [11] Barakat MA. (2011): New trends in removing heavy metals from industrial waste water. Arab. J. Chem. 4, 361–77. http://dx.doi.org/10.1016/j.arabjc.2010.07.019.

      [12] Bocca B, Forte G, Petrucci F, Cristaudo. (2007): Levels of nickel and other potentially allergenic metals in Ni-tested commercial body creams. J. Pharm. Biomed. Anal. 44, 1197– 202. http://dx.doi.org/10.1016/j.jpba.2007.04.031.

      [13] Bolann BJ, Rahil-Khazen R, Henriksen H, et al. (2007): Evaluation of methods for trace-element determination with emphasis on their usability in the clinical routine laboratory. Scand J Clin Lab Invest; 67: 353–366. http://dx.doi.org/10.1080/00365510601095281.

      [14] Bolduc C., Shapiro J (2001): Hair care products: waving, straightening, conditioning, and coloring, Clinics in Dermatology, 19 (4), 431 – 6. http://dx.doi.org/10.1016/S0738-081X(01)00201-2.

      [15] Brancaccio RR, Brown LH, Chang YC, Fogelman JP, Mafong EA, Cohen DE. (2002): Identification and Quantification of Para-Phenylenediamine in a Temporary Black Henna Tattoo. Am. J. Contact Dermot; 13:15 – 8. http://dx.doi.org/10.1053/ajcd.2002.30466.

      [16] Brandao JDO, Okonkwo OJ, Sehkula M, Raseleka RM. (2012): Concentrations of lead in cosmetics commonly used in South Africa. Toxicol Environ Chem; 94:70–7. http://dx.doi.org/10.1080/02772248.2011.633911.

      [17] Brown, V.J., (2013): Metals in lip products a cause for concern? Environ. Health Perspect. 121, A196. http://dx.doi.org/10.1289/ehp.121-a196.

      [18] CDC, Centres for Disease Control and Prevention (2003): Second National Report on Human Exposure to Environmental Chemicals. http://www.cdc.gov/exposurereport/2nd.

      [19] Charles Z. (1986): The Science of hair care, Marcel Dekker Inc., Madison Avenue, New York, NY 10016, U.S.A. pp 409 – 14.

      [20] Darbre PD. (2003): Underarm cosmetic and breast cancer. J. Appl. Toxicol. 23 (2), 89–95. http://dx.doi.org/10.1002/jat.899.

      [21] EC (2003): Directive 2003/15/EC of the European Parliament and of the Council of 27 February 2003 amending Council Directive 76/768/EEC on the approximation of the laws of the Member States relating to cosmetic products Official Journal of the European Union, 11.3.2003, L 66: 26-35.

      [22] Groot ACD, Nater JP, Weyland JW. (1994): Unwanted Effects of Cosmetics and Drugs Used in Dermatology, third ed. (issue 1). Elsevier, pp. 2–15.

      [23] Hatem Abdel Moniem Ahmed, Ragaa Mohamed Abdel Maaboud and, Fathy Fahim Abdul Latif et al. (2013): Different Analytical Methods of Para-Phenylenediamine Based Hair Dye. Journal of Cosmetics, Dermatological Sciences and Applications; 3: 17-25. http://dx.doi.org/10.4236/jcdsa.2013.33A1003.

      [24] Health Canada, Consumer product safety, (2011): Draft guidance on heavy metal impurities in cosmetics. Available: http://www.hcsc.gc.ca/cpsspc/legislation/consultation/_cosmt./metalmtauxconsulteng php.

      [25] J. H. Draize, (1944): Methods for study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Experim. Therapeutics 82: 377- 90.

      [26] Kumar S, Singh VV, Singh M. (2005): Agro-History, Uses, Ecology and Distribution of Henna (Lawsonia inermis L. syn. Alba Lam), Henna Cultivation, Improvement and Trade, 11- 12; Jodhpur, India.

      [27] Lahsissene H, Kahouadji A. (2010): Ethno botanical study of medicinal and aromatic plants in the Zaer region of Morocco. Phytother. 8: 202 – 9. http://dx.doi.org/10.1007/s10298-010-0569-2.

      [28] Marcelo E. Conti, Francesco Botre, Franco Mazzei (1996): On the heavy metals content in cosmetic formulations: an atomic absorption spectroscopy investigation, J. Appl. Cosmetol. 14: 147-54.

      [29] Nawaf AM, Joshi A, Nour-Eldin O. (2003): Acute allergic contact dermatitis due to Para-phenylenediamine after temporary henna painting. J Dermatol; 30:797–800. http://dx.doi.org/10.1111/j.1346-8138.2003.tb00480.x.

      [30] Neri I, Guareschi E, Savoia F, Patrizi A. (2002): Childhood Allergic Contact Dermatitis from Henna Tattoo. Pediat Dermatol; 19:503–5. http://dx.doi.org/10.1046/j.1525-1470.2002.00219.x.

      [31] Omolaoye JA, Uzairu A, Gimba CE. (2010): Heavy metal assessment of some eye shadow products imported into Nigeria from China. Arch Appl Sci Res; 2 (5): 76-84.

      [32] Oztas MO, Onder M, Oztaş P, Atahan C. (2001): Contact allergy to henna. J Eur Acad Dermatol Venereol; 15:91–2. http://dx.doi.org/10.1046/j.1468-3083.2001.00205-13.x.

      [33] Redlick F, Dekoven J. (2007): Allergic contact dermatitis to paraphenylene diamine in hair dye after sensitization from black henna tattoos: a report of 6 cases. Can Med Assn J; 176:445–6. http://dx.doi.org/10.1503/cmaj.061109.

      [34] Roy P K, Singh M, Tewari P. (2005): "Composition of Henna Powder, Quality Parameters and Changing Trends in its Usageâ€. Henna: Cultivation, Improvement, and Trade. Jodhpur: Central Arid Zone Research Institute; pp. 39–40.

      [35] Saeed M, Muhammad N, Khan H, Khan SA. (2010): Analysis of toxic heavy metals in branded Pakistani herbal products. J. Chem. Soc. Pak. 32, 471–5.

      [36] Sainio E. L., Jolanki R., Hakala E., Kanerva L. (2000): Metals and arsenic in eye shadows. Contact Dermatitis 42:5–10. http://dx.doi.org/10.1034/j.1600-0536.2000.042001005.x.

      [37] Scientific Committee on Consumer Products (SCCP, 2006): Opinion on P-phenylenediamine. In (Public Health and Risk Assessment) 9th plenary meeting, Brussels, Belgium.

      [38] Theresa OC, Onebunne OC, Dorcas WA, Ajani OI. (2011): Potentially toxic metals exposure from body creams sold in Lagos, Nigeria. Researcher 3 (1), 30–7.

      [39] US FDA, United State Food Drug and Cosmetic Act on Hazardous Chemicals in Cosmetics (2011): Available: http://www.fda.gov/opacom/ laws/fdcact/fdctoc.htm.

      [40] Yagi H, El Hind AM, Khalil SI. (1994): Acute poisoning from hair dye. East Afr Med J 68: 404-11.

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  • How to Cite

    Younes Ibrahim Md, S., Abdel Maguid Md, R., & Khaled Al-Mazroua, M. (2016). Evaluation of metals content among different cosmetic products in the Arabian market. International Journal of Pharmacology and Toxicology, 4(1), 53-58. https://doi.org/10.14419/ijpt.v4i1.5942

    Received date: 2016-02-25

    Accepted date: 2016-03-20

    Published date: 2016-04-13