Pharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities

  • Authors

    • Shailaja Ande Jawaharlal Nehru Technological university, Hyderabad.
    • khadar Shaik Jawaharlal Nehru Technological university, Hyderabad.
    • Ravi Dharmoji Jawaharlal Nehru Technological university, Hyderabad.
    • Nisa Firdouse Jawaharlal Nehru Technological university, Hyderabad.
    • Anjum Mohd Jawaharlal Nehru Technological university, Hyderabad.
    • Sowmya Yelwarthi Jawaharlal Nehru Technological university, Hyderabad.
  • Analgesic, Ant-Pyretic, Anti-Inflammatory, Oxazine Sulphonamide Derivatives, Yeast, Carrageenan, Plethysmometer.
  • Oxazine heterocyclic compound containing one oxygen and one nitrogen atom. They possess different pharmacological activities like anticancer, anti-ulcer, antifungal, antithrombotic, antihypertensive, analgesic, anti-inflammatory etc. Oxazine Sulphonamide derivatives were investigated for anti-inflammatory, analgesic and anti-pyretic activities. It was evaluated for anti-inflammatory activity by carrageenan induced paw edema in rats using Plethysmometer and it also shows significant analgesic effect in male Albino mice. Antipyretic activity was also investigated.

  • References

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    Ande, S., Shaik, khadar, Dharmoji, R., Firdouse, N., Mohd, A., & Yelwarthi, S. (2016). Pharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities. International Journal of Pharmacology and Toxicology, 4(2), 111-114.