Pharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities

Authors

  • Shailaja Ande Jawaharlal Nehru Technological university, Hyderabad.
  • khadar Shaik Jawaharlal Nehru Technological university, Hyderabad.
  • Ravi Dharmoji Jawaharlal Nehru Technological university, Hyderabad.
  • Nisa Firdouse Jawaharlal Nehru Technological university, Hyderabad.
  • Anjum Mohd Jawaharlal Nehru Technological university, Hyderabad.
  • Sowmya Yelwarthi Jawaharlal Nehru Technological university, Hyderabad.

DOI:

https://doi.org/10.14419/ijpt.v4i2.6123

Published:

2016-06-08

Keywords:

Analgesic, Ant-Pyretic, Anti-Inflammatory, Oxazine Sulphonamide Derivatives, Yeast, Carrageenan, Plethysmometer.

Abstract

Oxazine heterocyclic compound containing one oxygen and one nitrogen atom. They possess different pharmacological activities like anticancer, anti-ulcer, antifungal, antithrombotic, antihypertensive, analgesic, anti-inflammatory etc. Oxazine Sulphonamide derivatives were investigated for anti-inflammatory, analgesic and anti-pyretic activities. It was evaluated for anti-inflammatory activity by carrageenan induced paw edema in rats using Plethysmometer and it also shows significant analgesic effect in male Albino mice. Antipyretic activity was also investigated.

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