Pharmacological evaluation of oxazine sulfonamide derivatives for anti-inflammatory, analgesic and antipyretic activities


  • Shailaja Ande Jawaharlal Nehru Technological university, Hyderabad.
  • khadar Shaik Jawaharlal Nehru Technological university, Hyderabad.
  • Ravi Dharmoji Jawaharlal Nehru Technological university, Hyderabad.
  • Nisa Firdouse Jawaharlal Nehru Technological university, Hyderabad.
  • Anjum Mohd Jawaharlal Nehru Technological university, Hyderabad.
  • Sowmya Yelwarthi Jawaharlal Nehru Technological university, Hyderabad.





Analgesic, Ant-Pyretic, Anti-Inflammatory, Oxazine Sulphonamide Derivatives, Yeast, Carrageenan, Plethysmometer.


Oxazine heterocyclic compound containing one oxygen and one nitrogen atom. They possess different pharmacological activities like anticancer, anti-ulcer, antifungal, antithrombotic, antihypertensive, analgesic, anti-inflammatory etc. Oxazine Sulphonamide derivatives were investigated for anti-inflammatory, analgesic and anti-pyretic activities. It was evaluated for anti-inflammatory activity by carrageenan induced paw edema in rats using Plethysmometer and it also shows significant analgesic effect in male Albino mice. Antipyretic activity was also investigated.


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