Haematological changes in Trypanosoma evansi infected cattle

  • Authors

    • S. Sivajothi Assistant Professor
    • B Sudhakara Reddy
    • K. Nalini Kumari
    • V. C. Rayulu
    2014-05-21
    https://doi.org/10.14419/ijsw.v2i1.2275
  • Abstract

    During the three years period of study twelve cross bred cattle were identified that they were suffering with clinical Trypanosomiasis. Up on clinical examination cattle had anorexia, fever, ocular discharges, dullness and enlarged lymph nodes. Stained peripheral blood examination revealed the presence of Trypanosoma evansi. Haematological abnormalities include decreased TEC, PCV, Hb and TLC values (P<0.01). The present leucopaenia was characterized by neutrophilia, eosinophilia and lymphocytopaenia (P>0.05).

    Keywords: Anaemia - Cattle - Haematology - Leucopaenia - T. evansi.

  • References

    1. S.Sivajothi, V.C.Rayulu, K.Sujatha, B.S.Reddy, Study of Histopathological Changes in Experimental Trypanosoma evansi Infected Rats. Proc Zool Soc, 2014a DOI 10.1007/s12595-014-0104-9.
    2. S.Sivajothi, V.C. Rayulu, B.S. Reddy, Development of Slide Enzyme Linked Immunosorbent Assay (SELISA) for Detection of Trypanosoma evansi Infection in Bovines. Journal of Advanced Veterinary Research Volume 2 (2012) 15-17.
    3. S.Sivajothi, V.C.Rayulu, P. Malakondaiah, D. Sreenivasulu, Diagnosis of Trypanosoma evansi in bovines by indirect ELISA. J Parasit Dis. 2014b, DOI 10.1007/s12639-014-0465-z.
    4. S.Sivajothi, V.C.Rayulu, B.S.Reddy, Haematological and biochemical changes in experimental Trypanosoma evansi infection in rabbits. Journal of parasitic diseases, 2013a, DOI 10.1007/s12639-013-0321-6.
    5. S.Sivajothi, V.C.Rayulu, P.Malakondaiah, D.Sreenivasulu, Colloidal Dye Immunobinding Assay for Detection of Trypanosoma evansi Antibodies in Animals, International Journal of Livestock Research. 2013b, Vol 3(3), 48-56.
    6. B.S.Reddy, K.N.Kumari, S.Sivajothi, Haemato-biochemical findings and thyroxin levels in canine demodicosis. Comp Clin Pathol. 2014, DOI 10.1007/s00580-014-1893-y.
    7. J.Naessens, H. Kitani, Y. Yagi, K.Sekikawa, F.Iraqqi, TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine T. congolense infection, Clinical and Experimental Immunology 139(3): (March 2005), 403-410, PMID: PMC 180 9320.
    8. V.O.Anosa, Haematology and biochemical changes in human and animal trypanosomiasis. Part II. Rev Elev Med Vet Pays Trop, 1988, 41: 151–164.
    9. K.Vickerman, L. Tetley, Biology and ultra-structure of trypanosomes in relation to pathogenesis. In: Pathogenecity of trypanosomes , Proceedings of a workshop, pp. 231- 31, ISBN 0- 88936-214-9, Nairobi, Kenya, November 20-23, 1978.
    10. S.A.Shehu, N.D.G. Ibrahim, K.A.N.Esievo, G.Mohammed, Role of erythrocyte surface sialic acid inducing anaemia in Savannah Brown bucks experimentally infected with Trypanosoma evansi, Veterenarski Arhiv 26(6): (October 2006), 521-530, ISSN 0372-5480.
    11. I.O. Igbokwe, Mechanisms of cellular injury in African trypanosomiasis, Veterinary Bulletin 64(7): (March 1994), 611-620, ISSN 1684-5315.
    12. F.W.Jennings, The anaemia of parasitic infections, Proceedings of the 7th International Conference of the World Association for the Advancement of Veterinary Parasitology, pp. 41-67, ISBN 0-12655 365- 3, Thessalonica, Greece, October 15-19, 1975.
    13. I.O.Igbokwe, C.O.Nwosu, Lack of correlation of anaemia with splenomegaly and hepatomegaly in Trypanosoma brucei and Trypanosoma congolense infections of rats. J Comp Pathol 1997;117:261-5
    14. M.A.Akanji, O.S. Adeyemi, S.O.Oguntoye, F. Sulyman, Psidium guajava extract reduces Trypanosomiasis associated lipid per-oxidation and raises glutathione concentra-tions in infected animals. EXCLI J 2009; 8:148-54.
    15. Abeer A. Abd El-Baky, Shaymaa I. Salem. Clinico pathological and Cytological Studies on Naturally Infected Camels and Experimentally Infected Rats with Trypanosoma evansi. World Applied Sciences Journal 14 (1): 42-50, 2011.
    16. Z.I.Chaudhary, J. Iqbal, Incidence, biochemical and haematological alterations induced by natural Trypanosomiasis in racing dromedary camels. Acta Trop, 2000, 77, 209-213
    17. V.O.Anosa, L.L. Logan - Henfrey, C.W. Wells, The haematology of T. congolense infection in cattle 11: Macrophages structure and function in adult Boran cattle. Comparative Haematology International, 1997a, 7:23 - 29.
    18. A.Abubakar, B.Iliyasu, A.B.Yusuf, A.C. Igweh, N.A.Onyekwelu, B.A.Shamaki, D.O.Afolayan, E.O.Ogbadoyi, Antitrypano-somal and haematological effects of selected Nigerian medicinal plants in Wistar rats. Biokemistri 2005; 17:95-9.
    19. J.T.Ekanem, O.M. Kolawole, O.C. Abbah, Trypanocidal potential of methanolic ex- tract of Bridelia ferruginea benth bark in Rattus novergicus. Afr J Biochem Res 2008; 2:45-50.
    20. F.A.Sulaiman, O.S. Adeyemi, Changes in haematological indices and protein concentrations in Trypanosoma brucei infected rats treated with homidium chloride and diminazene aceturate. EXCLI Journal, 2010, 9: 39-45.
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  • How to Cite

    Sivajothi, S., Sudhakara Reddy, B., Kumari, K. N., & Rayulu, V. C. (2014). Haematological changes in Trypanosoma evansi infected cattle. International Journal of Scientific World, 2(1), 27-30. https://doi.org/10.14419/ijsw.v2i1.2275

    Received date: 2014-03-23

    Accepted date: 2014-04-26

    Published date: 2014-05-21