Levels of serum copper and zinc in healthy adults from the west of Algeria
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2019-12-15 https://doi.org/10.14419/jes.v1i2.30107
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Copper, Zinc, Serum, DPASV, Healthy Adults. -
Abstract
Essential trace element include zinc (Zn) and copper (Cu) are essential elements that play an important role in the whole-body metabolism. They have been implicated to play important roles in immuno-physiologic functions. The concentration of these elements in human organism varies widely between geographical areas depending on its content in soil and plants, dietary intake, bioavailability and retention, mineral interactions and other factors. The aim of this study was to measure the alterations in serum trace element concentrations, including Zn and Cu in one hundred and fifteen healthy adults (fifty-two males and sixty-three females) living in the west of Algeria using differential pulse anodic stripping voltammetry (DPASV) on a hanging mercury drop electrode. The mean copper and zinc concentrations were 105.26±19.63 μg/dL and 79.44±10.28 μg/dL, respectively. Serum concentrations of these elements were in the same range as those found for populations of other European countries.
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References
[1] Turgut S, Hacıoğlu S, Emmungil G, Turgut G, Keskin A. (2009) Relations between Iron Deficiency Anemia and Serum Levels of Copper, Zinc, Cadmium and Lead. Polish J of Environ Stud 18, 273-277.
[2] Tapiero H, Tew KD. (2003) Trace elements in human physiology and pathology: zinc and metallothioneins. Biomed Pharmacother 57, 399-411. https://doi.org/10.1016/S0753-3322(03)00081-7.
[3] McCall KA, Huang C, Fierke CA. (2000) Function and mechanism of zinc metalloenzymes. J Nutr130, 1437S-1446S. https://doi.org/10.1093/jn/130.5.1437S.
[4] Yousef MI, El Hendy HA, El-Demerdash EI, Elagamy FM. (2002) Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats. Toxicology 175, 223-234. https://doi.org/10.1016/S0300-483X(02)00049-5.
[5] Jansen J, Karges W, Rink L. (2009) Zinc and diabetes-clinical links and molecular mechanisms. J. Nutr. Biochem 20:399-417. https://doi.org/10.1016/j.jnutbio.2009.01.009.
[6] Bae YS, Hill ND, Bibi Y, Dreiher J, Cohen AD. (2010) Innovative uses for zinc in dermatology. Dermatologic Clinics 28, 587-597. https://doi.org/10.1016/j.det.2010.03.006.
[7] Ricketts JR, Rothe MJ, Grant-Kels JM. (2010) Nutrition and psoriasis. Clinics in Dermatology 28, 615-626. https://doi.org/10.1016/j.clindermatol.2010.03.027.
[8] Melinda J, Albert C. (2010) Syndromes associated with nutritional deficiency and excess. Clinics in Dermatology 28, 669-685. https://doi.org/10.1016/j.clindermatol.2010.03.029.
[9] Takeda A, Tamano A. (2009) Insight into zinc signaling from dietary zinc deficiency. Brain Research Reviews 62, 33-44. https://doi.org/10.1016/j.brainresrev.2009.09.003.
[10] Gaetke LM, McClain CJ, Toleman CJ, Stuart MA. (2010) Yogurt protects against growth retardation in weanling rats fed diets high in phytic acid. J NutrBiochem 21, 147-152. https://doi.org/10.1016/j.jnutbio.2008.12.005.
[11] Guo S, Dipietro L.A. (2010) Factors Affecting Wound Healing. J. Dent. Res 89, 219–229. https://doi.org/10.1177/0022034509359125.
[12] Tabatabai MA, Eby WM, Singh KP. (2011) Hyperbolastic modeling of wound healing. Math Comput Model 53, 755-768. https://doi.org/10.1016/j.mcm.2010.10.013.
[13] Poo JL, Rosas-Romero R, RodrÃguez F. (1995) Serum zinc concentrations in two cohorts of 153 healthy subjects and 100 cirrhotic patients from Mexico City. Dig Dis 13, 136–142. https://doi.org/10.1159/000171495.
[14] Rocchi E, Borella P, Borghi A. (1994) Zinc and magnesium in liver cirrhosis. Eur J Clin. Invest 24, 149–155. https://doi.org/10.1111/j.1365-2362.1994.tb00980.x.
[15] Gür G, Bayraktar Y, Ozer D. (1998) Determination of hepatic zinc content in chronic liver disease due to hepatitis B virus. Hepatogastroenterology 45, 472–476.
[16] Barry M, Keeling PW, Feely J. (1990) Tissue zinc status and drug elimination in patients with chronic liver disease. Clin Sci 78, 547–549. https://doi.org/10.1042/cs0780547.
[17] Pramoolsinsap C, Promvanit N, Komindr S. (1994) Serum trace metals in chronic viral hepatitis and hepatocellular carcinoma in Thailand. J Gastroenterol 29, 610–615. https://doi.org/10.1007/BF02365444.
[18] Goode HF, Kelleher J, Walker BE. (1990) Relation between zinc status and hepatic functional reserve in patients with liver disease. Gut 31, 694–697. https://doi.org/10.1136/gut.31.6.694.
[19] Aaseth J, Smith-Kielland A, Thomassen Y. (1986) Selenium, alcohol and liver diseases. Ann Clin Res 18, 43–47.
[20] Ijuin H. (1998) Evaluation of pancreatic exocrine function and zinc absorption in alcoholism. Kurume. J Med 45, 1–5. https://doi.org/10.2739/kurumemedj.45.1.
[21] O’Halloran T.V, Culotta V.C. (2000) Metallochaperones, an Intracellular Shuttle Service for Metal Ions. J Biol Chem 275, 25057-25060. https://doi.org/10.1074/jbc.R000006200.
[22] La Fontaine S, Quinn J.M, Nakamoto S.S. (2002) Copper-dependent iron assimilation pathway in the model photosynthetic eukaryote Chlamydomonas reinhardtii. Eukaryotic Cell 1, 736-757. https://doi.org/10.1128/EC.1.5.736-757.2002.
[23] Linder MC, Hazegh-Azam M. (1996) Copper biochemistry and molecular biology. Am J Clin Nutr 63, 797S-811S. https://doi.org/10.1093/ajcn/63.5.797
[24] Jack H.K, Svetlana L. (2009) Copper Transport in Mammalian Cells: Special Care for a Metal with Special Needs. J Biol Chem 284, 25461-25465. https://doi.org/10.1074/jbc.R109.031286.
[25] Lobo V, Patil A, Phatak A, Chandra N. (2010) Free radicals, antioxidants and functional foods: Impact on human health. J Pharmacogn Rev 4, 118-126. https://doi.org/10.4103/0973-7847.70902.
[26] Angelova M, Asenova S, Nedkova V, Koleva-Kolarova R. (2011) Copper in the human organism. Trakia of Journal Sciences 9, 88-98.
[27] Kumar N, Low PA. (2004) Myeloneuropathy and anemia due to copper malabsorption. J Neurol 251, 747–749. https://doi.org/10.1007/s00415-004-0428-x.
[28] Relling DP. (2007) Dietary interaction of high fat and marginal copper deficiency on cardiac contractile function. Obesity Silver Spring 15, 1242–1257. https://doi.org/10.1038/oby.2007.146.
[29] Araya M, Pizarro F, Olivares M, Arredondo M, Gonzalez M. (2006) Understanding copper homeostasis in humans and copper effects on health. Biol Res39, 183-187. https://doi.org/10.4067/S0716-97602006000100020.
[30] Bonham M, Jacqueline M, Bernadette MH, Strain JJ. (2002) The immune system as a physiological indicator of marginal copper status. British Journal of Nutrition 87, 393–403. https://doi.org/10.1079/BJN2002558.
[31] Malave I, Rodriguez J, Araujo Z, Rojas I. (1990) Effect of zinc on the proliferative, response of human lymphoeytes: Mechanism of its nitrogenic action. Immunopharmacology 20, 1-10. https://doi.org/10.1016/0162-3109(90)90002-V.
[32] HO E. (2004) Zinc deficiency, DNA damage and cancer risk. J NutrBiochem 15, 572-578. https://doi.org/10.1016/j.jnutbio.2004.07.005.
[33] Attar T, Larabi L. Harek Y. (2012) Determination of copper levels in whole blood of healthy subjects by anodic stripping voltammetry. International Journal of Analytical and Bioanalytical Chemistry 2, 160-164.
[34] Attar T, Larabi L, Harek Y. (2013) Determination of Zinc levels in Healthy Adults from the West of Algeria by Differential Pulse Anodic Stripping Voltammetry. Journal of Advances in Chemistry 6, 855-860. https://doi.org/10.24297/jac.v6i1.964.
[35] Attar T. (2019) Determination of serum cadmium and lead in healthy adults from the west of Algeria. SPC Journal of Environmental Sciences1, 12-15. https://doi.org/10.14419/jes.v1i2.29769
[36] Attar T, Larabi L. Harek Y. (2013) Determination of Ultra Trace Levels of Copper in Whole Blood by Adsorptive Stripping Voltammetry. J Korean Chem Soc7, 568-573. https://doi.org/10.5012/jkcs.2013.57.5.568.
[37] Romero C.D, Sanchez P.H, Blanco F.L, Rodriguez E.R, Majem L.S. (2002) Serum copper and zinc concentrations in a representative sample of the Canarian population. J Trace Med Biol16, 75-81. https://doi.org/10.1016/S0946-672X(02)80032-3.
[38] Rukgauer M, Klein J, Kruse-Jarres J.D. (1997) Reference values for trace elements copper, manganese, selenium and zinc in the serum/plasma of children, adolescents and adults. J Trace Element 11, 92-98. https://doi.org/10.1016/S0946-672X(97)80032-6.
[39] Kouremenou-Dona E, Dona A, Papoutsis J, Spiliopoulou C. (2006) Copper and zinc concentrations in serum of healthy Greek adults. Sci Total Environ 359, 76-81. https://doi.org/10.1016/j.scitotenv.2005.04.009.
[40] Vural H, Uzun K, Kocyigit A, Hgli A, Akyol O. (2000) Concentrations of copper, zinc and various elements in serum of patients with bronchial asthma. Trace Element Med Biol 14, 88-91. https://doi.org/10.1016/S0946-672X(00)80036-X.
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How to Cite
Attar, T. (2019). Levels of serum copper and zinc in healthy adults from the west of Algeria. SPC Journal of Environmental Sciences, 1(2), 26-28. https://doi.org/10.14419/jes.v1i2.30107Received date: 2019-11-08
Accepted date: 2019-11-30
Published date: 2019-12-15