Assessment of knowledge, perception of resident doctors regarding antibiotic resistance and prescription practice at zagazig university hospital, 2013

  • Authors

    • Maha Eltwansy community medicine departement , Faculty of medicine Zagazig university
    • Ghada Salem community medicine departement , Faculty of medicine Zagazig university
    2014-09-07
    https://doi.org/10.14419/ijbas.v3i4.3089

  • Abstract

    Background: Antibiotics are among the most frequently prescribed drugs worldwide. The overuse and/ or misuse of antibiotics can result in significant consequences as antimicrobial resistance, therapeutic failures, drug toxicities and drug interactions. Since antibiotics are medications that mainly prescribed by physicians, any action aimed at improving use of antimicrobials must necessarily target physicians.

    Objectives: To assess knowledge, perception and practice of the resident doctors about antibiotic resistance and antibiotic prescription at Zagazig University Hospital and to identify factors affecting them.

    Methodology: A cross-sectional survey was done at Zagazig University teaching hospital between July and September 2013. Self-administrated questionnaire were used to assess resident doctors' knowledge, perception and practice about antibiotics. Results: From 195 target physicians, 175 agreed to participate. The mean score of knowledge about quiz answer, perception about resistance and perception about prescription were (3.6, 3.8, and 3.2 respectively). The age of the resident doctors was statistically significant affecting answering of the eight quizzes and in the perception about antibiotics resistance (P=0.00) The answering of the eight quizzes, perception about antibiotics resistance and perception about antimicrobial prescription were significantly higher among male doctors than female doctors (P=0.000). There was also significant association between experience (> 2years) and the answering of the eight quizzes, perception about antibiotics resistance (P=0.000). Age groups, answering of the eight quizzes, the perception about antibiotics resistance and perception about antimicrobial prescription were statistically significantly affecting practice of resident doctors about antibiotic prescription ( P<0.05).

    Conclusion: This study concluded that knowledge of resident doctors and perception about antibiotic prescription was suboptimal. The perception about antibiotic resistance was very high, while doctors’ practice in prescribing antibiotic was satisfactory.

    Keywords: Antibiotic Resistance, Antibiotic Prescription, Resident Doctors, Perception, Knowledge.

  • References

    1. Olivier C, Willimas-Jones B, Doize B, Ozdemir V, "Containing Global Antibiotic Resistance: Ethical Drug Promotion in the Developing World. In: Sosa A, Byarugaba D, Amabile-Cuevas C, Hsueh P, Kariuki S et al.., editors. Antimicrobial resistance in developing countries". First ed. New York: Springer, (2010), pp: 505–524.
    2. Ozkurt Z, Erol S, Kadanali A, Ertek M, Ozden K, Tasyaran MA, "Change in antibiotic use, cost and consumption after an antibiotic restriction policy applied by infectious disease specialist", Journal Infection Disease, Vol.58, (2005), pp:338-43.
    3. Okeke I, "Poverty and root causes of resistance in developing countries. In: Sosa A, Byarugaba D, Amabile-Cuevas C, Hsueh P, Kariuki S et al. ., editors. Antimicrobial resistance in developing countries". First Ed. New York: Springer, (2010), pp:27–36. http://link.springer.com/chapter/10.1007%2F978-0-387-89370-9_3#page-1
    4. WHO (2012): The evolving threat of antimicrobial resistance: options for action.
    5. Srinivasan A, Song X, Richards A, Sinkowitz-Cochran R, Cardo D, Rand C, "A Survey of Knowledge, Attitudes, and Beliefs of House Staff Physicians From Various Specialties Concerning Antimicrobial Use and Resistance". Archives Internal Medicine; Vol.164, N.13, (2004), pp:1451-1456. http://archinte.jamanetwork.com/article.aspx?articleid=217189
    6. Tunger O, Karakaya Y, Cetin CB, Dinc G, Borand H, "Rational antibiotic use. Journal Infection Developing Countries"; Vol.3, (2009), pp:88–93. http://www.jidc.org/index.php/journal/article/view/19755736
    7. Kheder S I, "Physicians' Knowledge and Perception of Antimicrobial Resistance: A Survey in Khartoum State Hospital Settings". British Journal of Pharmaceutical Research; Vol.3, N.3, (2013), pp:347-362. http://www.sciencedomain.org/abstract.php?iid=211&id=14&aid=1159#.VAoBQsKSwgA
    8. Woolf SH, "Practice guidelines: a new reality in medicine: III. Impact on patient care". Archives Internal Medicine; Vol.153, (1993), pp: 2646-55. http://www.sciencedomain.org/abstract.php?iid=211&id=14&aid=1159#.VAoBosKSwgB
    9. Cabana MDR and CSP owe NR, "Why don't physicians follow clinical practice guidelines?a framework for improvement". JAMA; Vol.282, (1999), pp:1458- 1465.
    10. Jean C L, MarieH N, Carine R, Oscar R P., et al, "Antibiotic use: knowledge and perceptions in two university hospitals". Journal of Antimicrobial Chemotherapy; vol.66, N. 4, (2013), pp:936-940.
    11. Thriemer K, Katuala Y and Jacobs J Antibiotic Prescribing in DR Congo: "A Knowledge, Attitude and Practice Survey among Medical DoctorsandStudents".PLoSOne;Vol.8,N.2,(2013),e55495. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0055495.
    12. Garcia C, Llamocca LP, Garcia K, Jimenez A, Samalvides F, et al.: Knowledge, attitudes and practice survey about antimicrobial resistance and prescribing among physicians in a hospital setting in Lima, Peru. BMC clinical pharmacology 2011, 11: 18.
    13. Wester CW, Durairaj L., Evans AT, Schwartz DN, Husain S and Martinez E, Antibiotic resistance: a survey of physician perceptions. Archives Internal Medicine; Vol.162, (2002), pp:2210- 2216.
    14. Nagvi A and Pulcini C, "Bacterial resistance and antibiotic prescription: a survey of hospital physician perception, attitude, and knowledge". Med Mal Infect Nov; Vol.40, N. 11, (2010), pp:625-31.
    15. Navarro-San Francisco C, Del Toro M.D, Cobo, Javier C & José H et al., Knowledge and perceptions of junior and senior Spanish resident doctors about antibiotic use and resistance: Results of a multicenter survey. Enfermedades Infecciosas y Microbiología Clínica; Vol.31,(2013), pp:199-204.
    16. Giblin TB, Sinkowitz-Cochran RL, Harris PL, Jacobs S, Liberatore K, et al.:"Clinicians' perceptions of the problem of antimicrobial resistance in health care facilities". Archives of internal medicine. Vol. 164, (2004), pp:1662–1668.
    17. Abdullah M, Zaki, Salah I and Kheder, "Attribute and preference of doctors at primary health care centers in Khartoum State towards antibiotic prescribing". Khartoum Pharmacy Journal; Vol.14, N. 1, (2011), pp:6-10.
    18. Pulcini C, Williams F, Molinari N, Davey P and Nathwani D, "Junior doctors' knowledge and perceptions of antibiotic resistance and prescribing: a survey in France and Scotland". Clinical Microbiological Infection; Vol.17, (2011), pp:80–87
    19. Carla Morales Guerra C M, Pereira C A P, Neto ARN, Cardo D M and Correa L, "Physicians' Perceptions, Beliefs, Attitudes, and Knowledge Concerning Antimicrobial Resistance in a Brazilian Teaching Hospital". Infection Control and Hospital Epidemiology. Vol.28, (2007), p:12.

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    Eltwansy, M., & Salem, G. (2014). Assessment of knowledge, perception of resident doctors regarding antibiotic resistance and prescription practice at zagazig university hospital, 2013. International Journal of Basic and Applied Sciences, 3(4), 363-371. https://doi.org/10.14419/ijbas.v3i4.3089

    Received date: 2014-06-27

    Accepted date: 2014-07-26

    Published date: 2014-09-07