Stimulating electrode Design for Implantable Sub Retina Research Application: A Novel Approach

  • Authors

    • T Alavanthar
    • V Ellappan
    2018-04-25
    https://doi.org/10.14419/ijet.v7i2.24.12509
  • Microelectrode, electrode electrolyte, Artificial retina, Prosthesis, Bionic eye, Bio implant.

  • Abstract

    This paper aims to study and converse the theoretical model of neural stimulation implant electrodes with the electrochemical aspects of design. The study investigates the practically realizable hypothetical model of minimal invasive retinal implant (miRI) stimulating electrodes for restoring lost sight of patients blinded by degenerative retinal diseases. The basic elemental methods of charge injection by the stimulation electrode to tissue are pointed out.  A prologue on the developments of vision implants and electrode characteristics were presented. We communicated the most important factors considered in this design stage of modeling, such as electrode position, size, impedance, charge injection capability, temperature change of the targeted retinal tissue and it’s surrounding for vision implant system. In this design, a mathematical model is created to investigate for the all above said factors which influence implants positioned at internal surface of the retinal tissue. This investigation gives an initial step in design verification before the fabrication.

     

     

  • References

    1. [1] T. Alavanthar “Conceptual-Level Bio-Inspired Retinal Design Using Analogue Vlsi Systems†Int. J. Biomedical Engineering And Technology, Vol. 20, No. 1,P(51-65), 2016.

      [2] Keerthi Raja Manikanda Raja, Theenathayalan Alavanthar, S. K. Pandiyan†Analysis Of Primate Retinal System For Better Computational Modeling†Indian Journal Of Science And Technology, Volume 8, Issue 35,P, 2015

      [3] Keerthi Raja Manikanda Raja, Theenathayalan Alavanthar, S. K. Pandiyan â€Analysis Of Computational Model Of Primate Retinal System For Better Devising†International Conference On Electrical Science , 2013.

      [4] T. Alavanthar “Simulating Human Cones: A Survey “Journal Of Applied Sciences Research, Vol 9, No 4,P (2636-2638), 2013.

      [5] T. Alavanthar , V.Ellappan “Photovoltaic Cells Design for Sub Retinal Research Application: A Theoretical Approach†IEEE-conference , paper id: ICEDSS2018044, march 2018, unpublished.

      [6] Sri Harsha Kasi Raj “Analysis of Factors Affecting the Performance of Retinal Prostheses Using Finite Element Modelling of Electric Field Distribution in the Retina†PhD Thesis, Microtechnology and Microsystems Swiss Federal Institute of Technology (EPF Lausanne) Lausanne, Switzerland, June 2011

      [7] Humayun MS, Prince M, de Juan E Jr, Barron Y, Moskowitz M, Klock IB & Milam AH “Morphometric analysis of the extramacular retina from postmortem eyes with retinitis pigmentosa†Invest Ophthalmol Vis Sci 40: 143–148,1999.

      [8] Santos A, Humayun MS, de Juan E Jr, Greenburg RJ, Marsh MJ, Klock IB & Milam AH Preservation of the inner retina in retinitis pigmentosa. A morphometric analysis. Arch Ophthalmol 115: 511–515,1997

      [9] Stone JL, Barlow WE, Humayun MS, de Juan E Jr & Milam AH : Morphometric analysis of macular photoreceptors and ganglion cells in retinas with retinitis pigmentosa. Arch Ophthalmol 110: 1634–1639,1992.

      [10] S. Biswas,S. Das, M. Mahadevappa “stimulation of Electrode-Tissue Interface with Biphasic Pulse Train for Epiretinal Prosthesis†Excerpt from the Proceedings of the 2013 COMSOL Conference in Bangalore

      [11] Mahmut Emin CELIK, Irfan KARAGOz Simulation of Electrical Stimulation of Layered Retina with Bipolar Electrode Configuration and Temperature Change on the Retina†International Journal of Computational and Experimental Science and Engineering (IJCESEN) Vol. 1-No.1 (2015) pp. 5-7

      [12] Mahmut Emin “The Effect of the Electrical Stimulation on Temperature Rise in the Retinal Tissue for Visual Prostheses†International Journal of Computer and Electrical Engineering, Vol. 6, No. 4, August 2014

      [13] Mohit N Shivdasani et,all. “Evaluation of stimulus parameters and electrode geometry for an effective suprachoroidal retinal prosthesis†J. Neural Eng. Vol-7 (2010) (1- 11pp)

      [14] Samip Shah“Electrical properties of retinal–electrode interface†J. Neural Eng. Vol-4 (2007) S24–S29

      [15] Bryan Howellâ€Influences of Interpolation Error, Electrode Geometry, and the Electrode–Tissue Interface on Models of Electric Fields Produced by Deep Brain Stimulation†IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, VOL. 61, NO. 2, FEBRUARY 2014

      [16] Stuart F. Cogan “ELECTROCHEMICAL PRINCIPLES OF SAFE CHARGE INJECTION†chapter 3, Neurobionics,The Biomedical Engineering of Neural Prostheses, First Edition. Edited by Robert K. Shepherd., 2016 John Wiley & Sons pp 55-88

      [17] Donald R Cantrell “Incorporation of the electrode–electrolyte interface into finite-element models of metal microelectrodes†J. Neural Eng. 5 (2008) 54–67

      [18] Joyce Tombran-Tink, Colin J. Barnstable,Joseph F. Rizzo Iii [2007] Visual Prosthesis And Ophthalmic Devices: New Hope In Sight, Humana Press Inc. New Jersey 07512, Eisbn 978-1-59745-449-0

      [19] Sterling, P. "Some Principles Of Retinal Design: The Proctor Lecture", Investigative Ophthalmology & Visual Science†*2013.

      [20] Frank Rattay, Hassan Bassereh, Andreas Fellner. "Impact of Electrode Position on the Elicitation of Sodium Spikes in Retinal Bipolar Cells", Scientific Reports, 2017

  • Downloads

  • How to Cite

    Alavanthar, T., & Ellappan, V. (2018). Stimulating electrode Design for Implantable Sub Retina Research Application: A Novel Approach. International Journal of Engineering & Technology, 7(2.24), 570-577. https://doi.org/10.14419/ijet.v7i2.24.12509

    Received date: 2018-05-05

    Accepted date: 2018-05-05

    Published date: 2018-04-25