Morphological Aspects of Absorption of Antibodies

  • Authors

    • Nikolay N. Shulga
    • Nikolay M. Mandro
    • Galina A. Gavrilova
    • Alexey N. Chubin
    • Irina Yu. Sayapina
    • Yuriy A. Gavrilov
    • Lopsondorzho V. Hibchenov
    • Natal'ya V. Trush
    2018-07-07
    https://doi.org/10.14419/ijet.v7i3.12.16133
  • absorption, antibodies, small intestine, enterocytes, stem cell, villus.

  • Abstract

    Placenta, depending on the species histological features, may interfere or promote the transmission of antibodies in the mother-fetus system. There are several types of placentas: epithelial type (horses, donkeys and pigs), desmochoric type (cows, sheep and goats), endothelial type (rabbits, Guinea pigs), hemochorial type (monkeys and women). Desmochoric  and epithelial type of the placenta block the transfer of circulating maternal antibodies to the fetus. In animals with these types of placentae transfer of maternal antibodies to offspring is carried out by colostrum. Hemochorionic and endothelial chorionic placentae provides active transport of antibodies from the mother's bloodstream into the bloodstream of the fetus. Therefore, newborns have a complete set of maternal antibodies. The aim of our study was to investigate the mechanism of absorption of antibodies from colostrum by the epithelial cells of the small intestine of newborn animals with epithelial  and desmochoric  types of placentas. The article presents the results of the absorption of antibodies by epithelial cells of the small intestine of newborn animals with colostrum - type transmission of immune proteins from mother-offspring.  Thus, it was established that the absorption of antibodies by epithelial cells of the small intestine is limited in time (24-72 hours). The mechanism of absorption is the fetal structure of the epithelial cells of the small intestine with the ability to absorb antibodies, and the termination of antibody absorption is associated with the replacement of fetal enterocytes by postnatal ones.

     

  • References

    1. [1] Kozlov, N. Ah. (2004) General histology. SPb: Publishing House "LAN". 224.

      [2] Kononov, G. A., Akatov, V. A., Pospelov, A. I., Smirnov, I. V. (1977). Veterinary obstetrics and gynecology. L ."The Kolos", 656.

      [3] Shulga, N. N. (2005). Influence of the level of colostral immunity on the safety of newborn calves. report. RAAS. â„– 4. 41- 42.

      [4] Shulga, N. N. (2005). Dynamics of immunoglobulins in the blood and colostrum of sows. Vestnik. RAAS. â„– 4. 58-59.

      [5] Shulga, N. N., Sokolnikova, T.V., Shulga, V.N. (2005). Dynamics of immunoglobulins in blood and cow colostrum after calving. Dairy and meat cattle breeding. No. 1. 24.

      [6] Kleikova, D. A., Shulga, D. A., (2011). Nanostructure of the small intestine in piglets and its role in protecting against bacteria. Pig breeding. No. 5. 52-54.

      [7] Alekhin, Yu. N., Jukov, M. S. (2017). Absorption of colostral immunoglobulins in calves with experimental intranal asphyxia. Science of Russia: Goals and Tasks, VI International Scientific Conference. December 10. Ekaterinburg. No. 6. Part 4. 41- 47.

      [8] Stott, G. H., & Fellah, A. (1983). Colostral Immunoglobulin Absorption Linearly Related to Concentration for Calves1. Journal of Dairy Science, 66(6), 1319-1328.

      [9] Nardone, A., Lacetera, N., Bernabucci, U., & Ronchi, B. (1997). Composition of colostrum from dairy heifers exposed to high air temperatures during late pregnancy and the early postpartum period1. Journal of Dairy Science, 80(5), 838-844.

      [10] Stott, G. H. (1980). Immunoglobulin Absorption in Calf Neonates with Special Considerations of Stress1. Journal of Dairy Science, 63(4), 681-688.

      [11] Besser, T. E., Szenci, O., & Gay, C. C. (1990). Decreased colostral immunoglobulin absorption in calves with postnatal respiratory acidosis. Journal of the American Veterinary Medical Association, 196(8), 1239-1243.

      [12] Alekhin, Yu. N. (2000). Endogenous intoxications in animals and their diagnostics (guideline). Voronezh.

      [13] Karakshev, A. V., Vyachev, E. P. (1973). Micromethods in clinical laboratory. Sofia: Medicina I Fizkultura, 114-115.

      [14] Nozdrachev, A. D. (1983). Physiology of the autonomic nervous system. Saint-Petersburg.

      [15] Kalniņa, I., & Toma, M. M. (2004). Use of the fluorescent probe DSM in studies of the structural and functional changes of the erythrocyte membrane. Journal of fluorescence, 14(1), 41-47.

      [16] Moog, F., & Yeh, K. Y. (1979). Pinocytosis persists in the ileum of hypophysectomized rats unless closure is induced by thyroxine or cortisone. Developmental biology, 69(1), 159-169.

      [17] Gorman, N. T. (1995). Immunologi. Textbook of veterinary internal medicine. End. S.C. Ettinger and E.C. Feldman. Philadelphia, London, Toronto, Montreal, Sudney, Tokyo: W.B. Saunders Co., Vol. 2.

      [18] Baranovsky, P. V., Danilishina, V. S. (1983). Laboratory work, â„– 5. 62-63.

      [19] Semotan, K., & Kalab, D. (1997). A new method of preparation of bovine colostral immunoglobulins for parenteral administration in calves. Veterinarni medicina, 42(9), 249-252.

      [20] Chekishev, V. M. (1977). Quantitative determination of immunoglobulins in blood sera of animals: method. Recommendations. Novosibirsk. 20.

      [21] Mancini, G., Cerbonare, A., Heremans, J. F. (1965). Immunochemistry. 2 (3), 235-254.

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  • How to Cite

    N. Shulga, N., M. Mandro, N., A. Gavrilova, G., N. Chubin, A., Yu. Sayapina, I., A. Gavrilov, Y., V. Hibchenov, L., & V. Trush, N. (2018). Morphological Aspects of Absorption of Antibodies. International Journal of Engineering & Technology, 7(3.5), 74-77. https://doi.org/10.14419/ijet.v7i3.12.16133

    Received date: 2018-07-23

    Accepted date: 2018-07-23

    Published date: 2018-07-07