Synthesis and Characterization of Cocozone Oil as Skin Care Ingredient

 
 
 
  • Abstract
  • Keywords
  • References
  • PDF
  • Abstract


    Cocozone Oil (CCO) is one of the ozonated oils, obtained by the ozonation process of Virgin Coconut Oil (VCO), that can be used as a material for skin care products. The purpose of this study was to determine: (1) the optimum time and ozone dose for CCO synthesis from VCO using ozonation; (2) the changes in physico-chemical properties of the oil; (3) the change in saturated-unsaturated fatty acids content and the existence any new substances in the CCO. The ozonation of VCO was carried out for 25 hours, with monitoring at the intervals of 4, 8, 12, 16, 20 and 25 hours, at a constant temperature (25 °C) with an ozone flow of 0.25 g/hr. From this study it can be concluded that: (1) The optimal time or dose of ozone required for the synthesis of CCO from VCO through the ozonation process was 25 hours or equivalent to 0.0208 gr O3/ml VCO, (2) Physico-chemical characteristics of the CCO produced: resulting acid value (AV) was 2.71 mg/gram i.e. an increase of 630%; the peroxide value (PV) obtained was 238,77 mgrek/kg i.e. increase  of 3,453 %; the Iodine value (IV) was 0 (zero) i.e. a decrease of 100%; and, the viscosity was 13.30 centipoice i.e. it rose 116%; (3) the total content of saturated fatty acid increased by 3.34%  whereas the unsaturated fatty acid decreased by 98.83; and based on the analysis results of 13C and 1H NMR spectra, the resultant CCO contains a new substance, that is aldehydes.

     

     


  • Keywords


    Ozonation, virgin coconut oil (VCO), cocozone oil (CCO), Ozonated oil, physicochemical Characteristic.

  • References


      [1] Bailey, P. S, Ozonation in Organic Chemistry, Volume 1, Olefinic Compounds. New York, Academic Press,(1978), pp: 220

      [2] Criegee, R, Mechanism of Ozonolisis, 14th ed., Angewandte Chemie Int: England, (1975), 87 (21), pp: 765-771.

      [3] Dayrit, F.M, “Coconut oil: atherogenic or not? (What therefore causes atherosclerosis?)”, Phil J Cardiol.31(3), pp: 97-104. 2003

      [4] Dayrit, F.M, “Review Lauric Acid is a Medium-Chain Fatty Acid, Coconut Oil is a Medium-Chain Triglyceride”, Philippine Journal of Science, 143 (2), pp: 157-166. 2014

      [5] Díaz, M.F, Núñez N, Quincose, D., Díaz, M., Hernández, F.,”Study of Three Systems of Ozonized Coconut Oil”, Ozone-Sci. Eng. 27, 1. 2005.

      [6] Diaz, M.F, Gavin, J.A, Gomez, M, Curtielles, V and Hernandez. F, “Study of Sunflower Oil Using ozonated H NMR and Microbiological Analysis”, Ozone Sci. Eng. 28 (1), pp:59-63. 2006

      [7] Enjarlis, Bismo, S., Slamet dan Roekmijati, W. S, “Studi pendahuluan ozonasi (katalitik dan non-katalitik) limbah cair karbofuran, Reaktor”, 10 (2), pp: 88-95. 2006.

      [8] Handayani Sri, Enjarlis, “Pemurnian Virgin Coconut Oil dengan Zeolit 3A sebagai Bahan Baku Obat Kulit”, Jurnal Bahan Alam Terbarukan (JBAT), 5(2).2016.

      [9] Jana Orsavova, Ladislava Misurcova, Jarmila Vavra Ambrozova, Robert Vicha, and Jiri Mlcek, ”Fatty Acids Composition of Vegetable Oils and Its Contribution to Dietary Energy Intake and Dependence of Cardiovascular Mortality on Dietary Intake of Fatty Acids”, International Journal of Moleculas Sciences, 16, pp:12871-12890, 2015.

      [10] Jardines D.,T. Correa, O. Ledea, Z. Zamora, A. Rosado, and J. Molerio, “Gas Chromatography Mass Spectrometry Profile of Urinary Organic Acid of Wistar Rats Orally Treated with Ozonized Unsaturated Triglycerides and Ozonized Sunflower Oil”, Journal Chomatorgr B Analyt Technol Biomed Life Sci. 783(2), pp: 517-525.2003.

      [11] Laura Boemeke, Aline Marcadenti, Fernanda Michielin Busnello, Catarina Bertaso Andreatta Gottschall, ”Effects of Coconut Oil on Human Health”, Journal of Endocrine and Metabolic Diseases, 5, pp: 84-87, 2015.

      [12] Langlais. B, David. A.R, and Brink D.R, Ozone in Water Treatment Application Engineering. Cooperative Research Report Florida. Lewis Publishing. 1991

      [13] Manisha Mandal Deb and Mandal Shyamapada,”Coconut (Cocos nucifera L: Arecaceae) In health promotion and disease prevention”. Asian Pacific Journal of Tropical Medicine; pp: 241-247. 2011.

      [14] Nathália. R. de Almeida, Adilson Beatriza, Ana Camila Micheletti, and Eduardo J. de Arrudab Ele, “Review Ozonized vegetable oils and therapeutic properties: A review”, The Electronic Journal of Chemistry Orbital, 4, (4), 2012.

      [15] Sega, A. I, Zanardi, L, Chiasserini, A, Gabbrielli, V, Bocci and V, Travagli, “Properties of sesame oil by detailed 1H and 13C NMR assignments before and after ozonation and their correlation with iodine value, peroxide value, and viscosity measurements”. Chemistry and Physics of Lipids, 163 (2), pp:148–156, 2010.

      [16] Soriano Jr, N.U, Migo V.P, Matsumura M, “Functional group analysis of sunflower oil methyl esters by FT-IR and NMR”. Chem. Phys. Lipids; 126, pp:133–140, 2003.

      [17] Sadowska. J, Johansson. B, Johannessen. E, Friman. R, Broniarz. P, Rosenholm, “Characterization of ozonated vegetable oils by spectroscopic and chromatographic methods” Chemistry and Physics of Lipids, 151, pp: 85–91, 2008.

      [18] Travagli. I, Zanardi. V, Bocci, “Topical applications of ozone and ozonated oils as anti-infective agents: an insight into the patent claims”. Recent Patents on Anti-Infective Drug Discovery, 4 (2), pp:142–130, 2009.

      [19] Vinod K Jain1, Naresh K, Kumawat, K, Shankar Rao, Z. Y, Khan Zafer, “A Review on Methods of Physical and Chemical Analysis Of Medicated Oil”, International Ayurvedic Medical Journal, 3, Issue 3, pp:843 – 849, 2015.

      [20] Yong, W.J.W.H, Ge L, Ng YF, Tan SN,”The chemical composition and biological properties of coconut (Cocos nucifera L)”, Molecules 14, pp:5144-5164.

      [21] Zanardi. V, Travagli. A, Gabbrielli. L, Chiasserini. V, Bocci, “Physico-chemical characterization of sesame oil derivatives”, Lipids, 43 (9), pp: 877–886, 2009.


 

View

Download

Article ID: 18415
 
DOI: 10.14419/ijet.v7i3.32.18415




Copyright © 2012-2015 Science Publishing Corporation Inc. All rights reserved.