Anxiety Disorders and Quality of Life Among Patients with Intracranial Tumour and Other Brain Disorders in a Malaysian Hospital

  • Authors

    • Priscilla Das
    • Nyi Nyi Naing
    • Nadia Wan Arfah
    • KON Noorjan
    • Yee Cheng Kueh
    • Kantha Rasalingam
    2018-11-30
    https://doi.org/10.14419/ijet.v7i4.28.24744
  • Anxiety, Quality of life, Brain tumour & Brain disorder.

  • Abstract

    The main objective of this study is to access the prevalence of anxiety disorders and its relationship with quality of life factors among intracranial tumour and other brain disorders in a Malaysian hospital. Methods: a cross-sectional research design was utilized in the study.  The research was conducted at the Kuala Lumpur Hospital, a tertiary referral center for brain cancer cases. Mini International Neuropsychiatric Interview (MINI) was used to access anxiety disorders and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQC30) questionnaire for quality of life among the patients. Results: A total of 100 intracranial tumour and other brain disorders patients were included in the study. The prevalence of anxiety disorders in our study sample ranged from 3% to 31%. Overall, compared to patients without anxiety disorders, neurological disorders with anxiety disorders reported impaired quality of life in terms of physical functioning, emotional functioning, role functioning, social functioning fatigue, pain, insomnia, appetite loss, diarrhea, nausea and vomiting and global health status. The conclusions of this study support the fact that, like other cancer patients, intracranial tumour and other brain disorders patients are vulnerable in progressing anxiety disorders that could affect their overall quality of life.

     

     

  • References

    1. [1] Narayanan VK, Patel & Price S (2012), High grade gliomas: Pathogenesis, management and prognosis. Neurosurgery 12.

      [2] Laperriere NL, Zuraw & Cairncross G (2002),(Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review. Radiother Oncol 64(3), 259-73.

      [3] Laws ER, et al (2003),Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project. J Neurosurg 99(3), 467-73.

      [4] Parney IF, Waldron JS & Parsa AT (2009), Flow cytometry and in vitro analysis of human glioma-associated macrophages. Laboratory investigation. J Neurosurg 110(3), 572-82.

      [5] Lienard A, MI, Libert Y, Delvaux N, Marchal S, Boniver J, Etienne AM, Klastersky J, Reynaert C, Scalliet P, Slachmuylder JL& Razavi D (2006), Factors that influence cancer patients’ anxiety following a medical consultation: impact of a communication skills training programme for physicians. Annals of Oncology 7,1450–1458.

      [6] Guo Y, et al (2006), The Diagnosis of Major Depression in Patients With Cancer: A Comparative Approach. Psychosomatics 47(5), 376-384.

      [7] Washington Dc (2000), American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, Fourth Edditon, Text Revision, American Psychiatric Association.

      [8] Sheehan DV, LY, Harnett-Sheehan K, Janavs J, Weiller E& Bonora LI , et al (1997), Reliability and validity of the Mini International Neuropsychiatric Interview (MINI): According to the SCID-P. European Psychiatry 12, 232-241.

      [9] Mukhtar F, Abdul Kadir Abu Bakar, Mazni Mat Junus, Azizul Awaludin, Salina Abdul Aziz, Marhaini Midin, Muhammad Fadzillah Abdul Razak, Nurashikin Ibrahim, Ang Kim Teng, Jasvindar Kaur, Hairul Anuar Hashim, Maniam Tambu & Noor Ani Ahmad (2012), A preliminary study on the specificity and sensitivity values and inter-rater reliability of Mini International Neuropsychiatric Interview (MINI) in Malaysia. ASEAN J Psychiatry 13, 157-64.

      [10] DanielW (1999), Biostatistics: A Foundation for Analysis in the Health Sciences . 7 ed. New York: John Wiley & Sons.

      [11] SpencerR, et al (2010), Anxiety Disorders in Advanced Cancer Patients: Correlates and Predictors of End of Life Outcomes. Cancer 116(7), 1810-1819.

      [12] Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A & Duez NJ, et al (1993), The European Organisation for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute 85, 365-376.

      [13] Mustapa N & Yian LG (2007), Pilot-testing the Malay version of the EORTC questionnaire. Singapore Nursing Journal (2), 16-20.

      [14] Fayers PM, AN, Bjordal K, Groenvold M, Curran D & Bottomley A, et al (2001), on behalf of the EORTC QLQ-C30 Scoring Manual (3rd Edition).

      [15] Mystakidou K, et al (2005), Assessment of Anxiety and Depression in Advanced Cancer Patients and their Relationship with Quality of Life. Quality of Life Research 14(8), 1825-1833.

      [16] Rasic DT, et al (2008), Cancer, mental disorders, suicidal ideation and attempts in a large community sample. Psycho-Oncology 17(7), 660-667.

      [17] Slaughter JR, et al (2000), Panic disorder in hospitalized cancer patients. Psycho-Oncology 9(3): 253-258.

      [18] van den Beuken-van Everdingen MHJ, et al (2009), Quality of Life and Non-Pain Symptoms in Patients with Cancer. Journal of Pain and Symptom Management 38(2), 216-233.

      [19] Moradi A, et al (2011), Treatment of Anxiety Disorder with Neurofeedback: Case Study. Procedia - Social and Behavioral Sciences 30, 103-107.

      [20] Zarghi A (2014), ( Assessment of Cognitive Impairments, Depression, Anxiety and Quality of Life among Brain Tumor Patients and Healthy Adults. International Clinical Neuroscience Journal 1(2).

      [21] Zarghi A, et al (2013), Cognitive and Mental Changes in Patients with Brain Tumor after Surgery. Global Journal of Surgery 1(3), 37-40.

      [22] Asbury FD, Findlay H & ReynoldsB (1998), A Canadian survey of cancer patients’ experiences: Are their needs being met? . J Pain Symptom Manage 16, 298-306.

      [23] Stark D, Kiely M, Smith G, Velikova G, House A & Selby P (2002), Anxiety disorders in cancer patients: their nature, association and relation to quality of life. Journal of Clinical Oncology 20, 3137-3148.

      [24] Deimling GT, et al (2006), Cancer-related health worries and psychological distress among older adult, long-term cancer survivors. Psycho-Oncology 15(4), 306-320.

      [25] Prieto JM, et al (2002), Psychiatric morbidity and impact on hospital length of stay among hematologic cancer patients receiving stem-cell transplantation. Journal of Clinical Oncology 20(7), 1907-1917.

      [26] Pamuk GE, et al (2008), EORTC QLQ-C30 assessment in Turkish patients with hematological malignancies: association with anxiety and depression. Annals of Hematology 87(4), 305-310.

      [27] Black EK & White CA(2005), Fear of recurrence, sense of coherence and posttraumatic stress disorder in haematological cancer survivors. Psycho-Oncology 14(6), 510-515.

      [28] Sampogna F, et al (2009), Quality of life and psychological distress in patients with cutaneous lymphoma. The British Journal Of Dermatology 160(4), 815-822.

      [29] Gan G, et al (2008), Bone marrow and stem cell transplantation: Malaysian experience. Bone Marrow Transplantation 1, S103-S105.

      [30] Sherry W, Fox, Debra Lyon&Farace E (2007), Symptom Clusters in Patients With High-Grade Glioma. Journal of nursing scholarship 39(1).

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  • How to Cite

    Das, P., Nyi Naing, N., Wan Arfah, N., Noorjan, K., Cheng Kueh, Y., & Rasalingam, K. (2018). Anxiety Disorders and Quality of Life Among Patients with Intracranial Tumour and Other Brain Disorders in a Malaysian Hospital. International Journal of Engineering & Technology, 7(4.28), 537-542. https://doi.org/10.14419/ijet.v7i4.28.24744

    Received date: 2018-12-25

    Accepted date: 2018-12-25

    Published date: 2018-11-30