The Effect of Different Concentration of 2-Methyl-4-Chlorophenoxy Acetate Acid on Graphite Oxide Intercalation Nanohybrid

 
 
 
  • Abstract
  • Keywords
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  • Abstract


    In this study, the effect of different concentration of 2-methyl-4-chlorophenoxy acetate acid (MCPA) was investigated to synthesis the successful intercalated herbicide nanohybrid by using graphite oxide (GO) as a nanocarrier. Through this experiment, a well-organized nanohybrid was obtained at the concentration of 0.3 M of MCPA. 2-methyl-4-chlorophenoxy acetate acid- graphite oxide (MCGO) nanohybrid was characterized by using FTIR, PXRD and CHNS. From the results obtained, the expansion of d-spacing of MCGO nanohybrid has indicated the presence of MCPA in the GO interlayer with the loading percentage around 98 %. Besides, FTIR spectra of the nanohybrid shown a resemblance peaks of the MCPA and GO that could confirm the formation of nanohybrid. Furthermore, the controlled release of MCPA into sodium carbonate solution (Na2CO3) was found to be reliant on concentration of Na2CO3 solution.

     

     

     


  • Keywords


    Graphite oxide; MCPA; Nanohybrid; Concentration; Herbicide.

  • References


      [1] G. Lalwani, M. D'Agati, A. M. Khan, and B. Sitharaman, "Toxicology of graphene-based nanomaterials," Advanced Drug Delivery Reviews, vol. 105, pp. 109-144, 2016

      [2] Wang, Y., Li, Z., Wang, J., Li, J., and Lin, Y. (2011). Graphene and graphene oxide : biofunctionalization and applications in biotechnology. Trends in Biotechnology, 29(5), 205–212

      [3] Meng, N., Zhang, S., and Zhou, N. (2010). Biopolymer-modified graphite oxide nanocomposite films based on benzalkonium chloride – heparin intercalated in graphite oxide, Nanotechnology.185101

      [4] Tran, T. H., Nguyen, H. T., and Pham, T. T. (2015). Development of a Graphene Oxide Nanocarrier for Dual-Drug Chemo-phototherapy to Overcome Drug Resistance in Cancer Article Development of a Graphene Oxide Nanocarrier for Dual-Drug Chemo- phototherapy to Overcome Drug Resistance in Cancer. Applied Materials & Interfaces

      [5] Yu, D., Ruan, P. A. N., Meng, Z., Zhou, J., and Ber, P. (2015). The Structure-Dependent Electric Release and Enhanced Oxidation of Drug in Graphene Oxide-Based Nanocarrier Loaded with. Journal of Pharmaceutical Sciences, 104(8), 2489–2500

      [6] Torbati, M. B., Ebrahimian, M., and Yousefi, M. (2016). GO-PEG as a drug nanocarrier and its antiproliferative effect on human cervical cancer cell line, 1401(April), 0–6.

      [7] Kumar, A., and Lee, C. H. (2013). Synthesis and Biomedical Applications of Graphene : Present and Future Trends. Wiley InterScience. Vol. 94, 1420–1427

      [8] Chowdhury, D. R., Singh, C., and Paul, a., (2014). RSC Advances graphite oxide synthesis, 15138–15145

      [9] Cao, Y., Li, G. and Li, X., (2016). Graphene / layered double hydroxide nanocomposite : Properties , synthesis , and applications. Chemical Engineering Journal, 292, 207–223.

      [10] Wu, Z., Ren, W., Gao, L., Liu, B., Jiang, C., and Cheng, H. (2008). Synthesis of high-quality graphene with a pre-determined number of layers. Carbon, 47(2), 493–499.

      [11] Jeong, H., Lee, Y. P., Jin, M. H., Kim, E. S., Bae, J. J., and Lee, Y. H. (2009). Thermal stability of graphite oxide. Chemical Physics Letters, 470(4–6), 255–258

      [12] Ceriotti, G., Romanchuk, A. Y., Slesarev, A. S. and Kalmykov, S. N., (2015). Rapid method for the purification of graphene oxide. RSC Adv., Nanoscale.5(62), 50365–50371.

      [13] Chen, J., Li, Y., Huang, L., Li, C., and Shi, G. (2014). High-yield preparation of graphene oxide from small graphite flakes via an improved Hummers method with a simple purification process. Carbon, 81, 826–834.

      [14] Chen, J., Yao, B., Li, C., and Shi, G. (2013). An improved Hummers method for eco-friendly synthesis of graphene oxide. Carbon, 64(1), 225–229

      [15] Liu, J., Cui, L., and Losic, D. (2013). Acta Biomaterialia Graphene and graphene oxide as new nanocarriers for drug delivery applications. Acta Biomaterialia, 9(12), 9243–9257.

      [16] Dorniani, D., Saifullah, B., Barahuie, F., Arulselvan, P., Zobir, M., Hussein, B. and Twyman, L. J. (2016). Graphene Oxide-Gallic Acid Nanodelivery System for Cancer Therapy. Nanoscale Research Letters.

      [17] Braterman, P. S., Xu, Z. P., Yarberry, F., Auerbach, S. M., & Carrado, K. a. (2004). Handbook of layered materials: layered double hydroxides, 373–474

      [18] Sarijo, Sheikh, S., Izaddin, A., and Mohd, S. (2012). Synthesis of nanocomposite 2-methyl4-chlorophenoxyacetic acid with layered double hydroxide : physicochemical characterization and controlled release properties, J Nanopart Res (3)

      [19] Sarijo, S. H., and Hussein, M. Z. (2015). Synthesis of dual herbicides-intercalated hydrotalcite-like nanohybrid compound with simultaneous controlled release property. Porous Mater.

      [20] Salleh N.M, Mohsin S.M.N, Sarijo S.H and Ghazali S.A.I.S.M. (2017). Synthesis and Physico-Chemical Properties of Zinc Layered Hydroxide-4-Chloro-2-Methylphenoxy Acetic Acid ( ZMCPA ). Materials Science and Engineering.

      [21] Barahuie, F., Saifullah, B., Dorniani, D., Fakurazi, S., Karthivashan, G., Zobir, M., and Elfghi, F. M. (2016). Graphene oxide as a nanocarrier for controlled release and targeted delivery of an anticancer active agent , chlorogenic acid. Materials Science & Engineering C, 74, 177–185.

      [22] Song, J., Wang, X., and Chang, C. (2014). Preparation and Characterization of Graphene Oxide, Journal of Nanomaterials. Volume 2014 : 276143, (6)

      [23] Zhang, L., Xia, J., Zhao, Q., Liu, L., and Zhang, Z. (2010). Functional Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Mixed Anticancer Drugs, 537–544.


 

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Article ID: 25684
 
DOI: 10.14419/ijet.v7i4.42.25684




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