Separation of Biological Molecules using Electrochemically Etched Nanoporous Silicon Membrane

  • Authors

    • Norhafizah Burham
    • Tuan Norjihan Tuan Yaakob
    • Azrul Azlan Hamzah
    • Burhannuddin Yeop Majlis
    2019-01-18
    https://doi.org/10.14419/ijet.v8i1.7.25948
  • Nanoporous silicon membrane, PDMS, electrochemical etching, biological molecules, indium oxide

  • Abstract

    This paper presents a separating technique of biological molecules and non-biological particles in solution using nanoporous silicon membranes. The simple separation method has been studied by fabricating the porous silicon membrane with Polydimethylsiloxane (PDMS) to produce the filtration system. The testing procedure began with diluted and sonicated indium oxide particles with deionized (DI) water and mixed with a biological solution. In this experiment setup, biological particles used is protein standard, serum albumin and sodium chloride has been filtered out through this filtration system. As a result, the indium oxide particles were trapped on the nanoporous silicon surface. Meanwhile, biology molecules penetrate the nanoporous silicon membrane with particle and molecule sizes up to 15 nm. The filtered-out particles are inspected under Zetasizer Nano SP to count and measure the size of the particles and molecules. According to the inspected result show 98% biological molecules are filtered out from this nanoporous silicon membrane. Due to this simple fabrication process, porous silicon membranes are able to be integrated to the other component to develop the complete bioMEMS and Lab on Chip system in the future.

     

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  • How to Cite

    Burham, N., Norjihan Tuan Yaakob, T., Azlan Hamzah, A., & Yeop Majlis, B. (2019). Separation of Biological Molecules using Electrochemically Etched Nanoporous Silicon Membrane. International Journal of Engineering & Technology, 8(1.7), 1-6. https://doi.org/10.14419/ijet.v8i1.7.25948

    Received date: 2019-01-16

    Accepted date: 2019-01-16

    Published date: 2019-01-18