Deep CNN based MR image denoising for tumor segmentation using watershed transform

  • Authors

    • Ghazanfar Latif
    • D N.F. Awang Iskandar
    • Jaafar Alghazo
    • Mohsin Butt
    • Adil H. Khan
    2018-03-08
    https://doi.org/10.14419/ijet.v7i2.3.9964
  • Deep CNN Denoising, Brain Tumor Segmentation, Anisotropic Diffusion, BraTS MRI, Rician Noise
  • Magnetic Resonance Imaging (MRI) is considered one of the most effective imaging techniques used in the medical field for both clinical investigation and diagnosis. This is due to the fact that MRI provides many critical features of the tissue including both physiological and chemical information. Rician noise affects MR images during acquisition thereby reducing the quality of the image and complicating the accurate diagnosis. In this paper, we propose a novel technique for MR image denoising using Deep Convolutional Neural Network (Deep CNN) and anisotropic diffusion (AD) which we will refer to as Deep CNN-AD. Watershed transform is then used to segment the tumorous portion of the denoised image.   The proposed method is tested on the BraTS MRI datasets. The proposed denoising method produced better results compared to previous methods. As denoising process affect the segmentation process therefore better denoised images by proposed technique produced more accurate segmentation with an average Specificity of 99.85% and dice coefficient of 90.46% thus indicating better performance of proposed technique.

  • References

    1. [1] Kural, C., Pusat, S., Åžentürk, T., Seçer, H.Ä°. and Ä°zci, Y., (2011),“Extracranial metastases of anaplastic oligodendrogliomaâ€, Journal of Clinical Neuroscience, 18(1), pp.136-138.

      [2] Louis, D.N., Ohgaki, H., Wiestler, O.D., Cavenee, W.K., Burger, P.C., Jouvet, A., Scheithauer, B.W. and Kleihues, P., (2007)“The 2007 WHO classification of tumours of the central nervous systemâ€, Acta neuropathologica, 114(2), pp.97-109.

      [3] Van Meir, E.G., Hadjipanayis, C.G., Norden, A.D., Shu, H.K., Wen, P.Y. and Olson, J.J., (2010),“Exciting new advances in neuroâ€oncology: The avenue to a cure for malignant gliomaâ€, CA: a cancer journal for clinicians, 60(3), pp.166-193.

      [4] Link, M.J. and Perry, A., (2009),“Meningioma Tumorigenesis: An Overview of Etiologic Factorsâ€, In Meningiomas (pp. 137-145). Springer London.

      [5] Nag, M.K., Koley, S., Chakraborty, C. and Sadhu, A.K., (2015),“Magnetic Resonance Image Quality Enhancement Using Transform Based Hybrid Filteringâ€, In Advancements of Medical Electronics (pp. 39-48). Springer, New Delhi.

      [6] Garg, S. and Kaur, J., (2013),“Improving segmentation by denoising brain MRI images through interpolation median filter in ADTVFCMâ€, International Journal of Computer Trends and Technology, 4(2), pp.187-188.

      [7] Khan, A., Alasad, J. and Latif, G., (2017),“Speckle Suppression in Medical Ultrasound Images through Schur Decompositionâ€, IET Image Processing.

      [8] Menze, B.H., Jakab, A., Bauer, S., Kalpathy-Cramer, J., Farahani, K., Kirby, J., Burren, Y., Porz, N., Slotboom, J., Wiest, R. and Lanczi, L., (2015),“The multimodal brain tumor image segmentation benchmark (BRATS)â€, IEEE transactions on medical imaging, 34(10), pp.1993-2024. Vancouver

      [9] Balafar, M.A., Ramli, A.R., Saripan, M.I. and Mashohor, S., (2010),“Review of brain MRI image segmentation methodsâ€, Artificial Intelligence Review, 33(3), pp.261-274.

      [10] M.A .Balafar, (2012), “Review of noise reducing algorithms for brain MRI imagesâ€, International Journal on Technical and Physical Problems of Engineering, Published by International Organization of IOTPE,Vol.4,Issue 13,No. 4,pp 54-59.

      [11] Perona, P. and Malik, J., (1990),“Scale-space and edge detection using anisotropic diffusionâ€, IEEE Transactions on pattern analysis and machine intelligence, 12(7), pp.629-639.

      [12] Jaffar, M. A., Zia, S., Latif, G., Mirza, A. M., Mehmood, I., Ejaz, N., &Baik, S. W. (2012),“Anisotropic diffusion based brain MRI segmentation and 3D reconstructionâ€, International Journal of Computational Intelligence Systems, 5(3), 494-504.

      [13] Luisier, F. and Wolfe, P.J., (2011), “Chi-square unbiased risk estimate for denoising magnitude MR imagesâ€, In Image Processing (ICIP), 2011 18th IEEE International Conference on (pp. 1561-1564). IEEE.

      [14] Buades, A., Coll, B. and Morel, J.M., (2005), “A non-local algorithm for image denoisingâ€, In Computer Vision and Pattern Recognition, 2005. CVPR 2005. IEEE Computer Society Conference on (Vol. 2, pp. 60-65). IEEE.

      [15] Tomasi C, Manduchi R (1998),“Bilateral filtering for gray and color imagesâ€, In Proceedings of the sixth international conference on computer vision, pp 839–846.

      [16] Prima, S. and Commowick, O., (2013),“Using bilateral symmetry to improve non-local means denoising of MR brain imagesâ€, In Biomedical Imaging (ISBI), 2013 IEEE 10th International Symposium on (pp. 1231-1234). IEEE.

      [17] Golshan, H.M. and Hasanzadeh, R.P., (2013),“A modified Rician LMMSE estimator for the restoration of magnitude MR imagesâ€,Optik-International Journal for Light and Electron Optics, 124(16), pp.2387-2392.

      [18] Manjón, J.V., Coupé, P., Buades, A., Collins, D.L. and Robles, M., (2012),“New methods for MRI denoising based on sparseness and self-similarityâ€, Medical image analysis, 16(1), pp.18-27.

      [19] Zhang, C., Hu, W., Jin, T. and Mei, Z., (2016),“Nonlocal image denoising via adaptive tensor nuclear norm minimizationâ€, Neural Computing and Applications, pp.1-17.

      [20] Sharif, M., Hussain, A., Jaffar, M.A. and Choi, T.S., (2015),“Fuzzy similarity based non local means filter for rician noise removalâ€, Multimedia tools and applications, 74(15), pp.5533-5556.

      [21] Pinheiro, P. and Collobert, R., (2014), “Recurrent convolutional neural networks for scene labelingâ€, In International Conference on Machine Learning, pp. 82-90.

      [22] Farabet, C., Couprie, C.,Najman, L. and LeCun, Y., (2013),“Learning hierarchical features for scene labelingâ€, IEEE transactions on pattern analysis and machine intelligence, 35(8), pp.1915-1929.

      [23] Long, J., Shelhamer, E. and Darrell, T., (2015)),“Fully convolutional networks for semantic segmentationâ€, In Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 3431-3440.

      [24] Havaei, M., Davy, A., Warde-Farley, D., Biard, A., Courville, A., Bengio, Y., Pal, C., Jodoin, P.M. and Larochelle, H., (2017),“Brain tumor segmentation with deep neural networksâ€, Medical image analysis, 35, pp.18-31.

      [25] Gauch, J.M., (1999),“Image segmentation and analysis via multiscale gradient watershed hierarchiesâ€, IEEE transactions on image processing, 8(1), pp.69-79.

      [26] Pal, C., Das, P., Chakrabarti, A., & Ghosh, R., (2017), “Rician noise removal in magnitude MRI images using efficient anisotropic diffusion filteringâ€, International Journal of Imaging Systems and Technology, 27(3), 248-264.

      [27] Zhang, K., Zuo, W., Chen, Y., Meng, D., & Zhang, L., (2017),“Beyond a gaussian denoiser: Residual learning of deep cnn for image denoisingâ€, IEEE Transactions on Image Processing.

      [28] Gao, W., Zhang, X., Yang, L., & Liu, H., (2010),“An improved Sobel edge detectionâ€, In 3rd International Conference on Computer Science and Information Technology (ICCSIT), Vol. 5, pp. 67-71, IEEE.

      [29] Latif, G., Iskandar, D. A., Jaffar, A., & Butt, M. M. (2017). Multimodal Brain Tumor Segmentation using Neighboring Image Features. Journal of Telecommunication, Electronic and Computer Engineering (JTEC), 9(2-9), 37-42.

      [30] Wiest-Daesslé, N., Prima, S., Coupé, P., Morrissey, S. P., &Barillot, C., (2008),“Rician noise removal by non-local means filtering for low signal-to-noise ratio MRI: applications to DT-MRIâ€, In International Conference on Medical Image Computing and Computer-assisted Intervention, pp. 171-179. Springer, Berlin, Heidelberg.

      [31] Havaei, M., Davy, A., Warde-Farley, D., Biard, A., Courville, A., Bengio, Y., ... & Larochelle, H, (2017),“Brain tumor segmentation with deep neural networksâ€, Medical image analysis, 35, pp. 18-31.

      [32] Pereira, S., Pinto, A., Alves, V., & Silva, C. A. (2016),“Brain tumor segmentation using convolutional neural networks in MRI imagesâ€, IEEE transactions on medical imaging, 35(5), pp. 1240-1251.

      [33] Kwon, D., Shinohara, R. T., Akbari, H., &Davatzikos, C., (2014),“Combining generative models for multifocal glioma segmentation and registrationâ€, In International Conference on Medical Image Computing and Computer-Assisted Intervention (pp. 763-770). Springer, Cham.

      [34] Bauer, S., Nolte, L. P., & Reyes, M., (2011),“Fully automatic segmentation of brain tumor images using support vector machine classification in combination with hierarchical conditional random field regularizationâ€, In International Conference on Medical Image Computing and Computer-Assisted Intervention (pp. 354-361). Springer, Berlin, Heidelberg.

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  • How to Cite

    Latif, G., N.F. Awang Iskandar, D., Alghazo, J., Butt, M., & H. Khan, A. (2018). Deep CNN based MR image denoising for tumor segmentation using watershed transform. International Journal of Engineering & Technology, 7(2.3), 37-42. https://doi.org/10.14419/ijet.v7i2.3.9964