DiGeorge syndrome and immune thrombocytopenia purpura

  • Authors

    • Amna Mohsin MRCP working in East and North Hertfordshire NHS trust ,previously working in Al Qassimi Hospital (MOHAP) and wrote article during that .
    • Mahasin Shaheen MD MRCP Al Qassimi Hospital (Ministry of Health and Prevention)
    2019-11-10
    https://doi.org/10.14419/ijm.v7i1.29732
  • Cleft Palate, Congenital Cardiac Anomalies, 22q11.2 Deletion, Digeorge Syndrome, Immune Thrombocytopenic Purpura, Purpuric Rash.
  • Digeorge Syndrome (22q11.2 deletion syndrome) comprises of various congenital anomalies such as cardiac defects, specific facial appearances, defective T cell production, hypocalcemia etc. This syndrome is also associated with various autoimmune diseases. Here we present a case report which shows association of Immune thrombocytopenia purpura with Digeorge Syndrome. A 15 years old boy born with congenital cardiac defects, diagnosed as 22q11.2 deletion syndrome, underwent corrective cardiac surgeries after birth. He developed thrombocytopenia at this age, requiring admission and platelet transfusions. His further work up confirmed Immune thrombocytopenic purpura and its presentation being related to the genetic disorder itself.

     

     

     
  • References

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    Mohsin MRCP, A., & Shaheen MD MRCP, M. (2019). DiGeorge syndrome and immune thrombocytopenia purpura. International Journal of Medicine, 7(1), 8-11. https://doi.org/10.14419/ijm.v7i1.29732