A revision on Urena lobata L.

  • Authors

    • Muhammad Islam LecturerDepartment of PharmacySouthern University BangladeshMehedibag-4000, Chittagong
    • Mohammad Uddin Department of PharmacySouthern University BangladeshMehedibag-4000, Chittagong
    2017-05-01
    https://doi.org/10.14419/ijm.v5i1.7525
  • Ethnopharmacological Uses, Phytoconstituents, Biological Activities.

  • The medicinal plant, Urena lobata L. (Malvaceae) is commonly known as aramina fibre, caesarweed or congo jute is widely distributed in Bangladesh. The ethnopharmacological usages of the parts of this plant are antique for the treatment of various diseases. In the recent years, a number of scientific evidences have been seen on its isolated phytochemicals and biological activities. This review offers a current scenario of the U. lobata, emphasized on the phyto-pharmacological findings. A search was made in the electronic databases such as PubMed, Science Direct and Google scholar for the published articles till January 31, 2017. To date, several important flavonoids, glycosides and terpenoids have been isolated from this plant. U. lobata possesses promising biological activities, including antioxidant, inflammatory, antimicrobial, anticancer, anti-diarrheal, anti-diabetic, anti-hyperlipidemic, neuropharmacological etc. U. lobata may be one of the good sources of therapeutic phytochemicals.

  • References

    1. [1] Adewale AO, David AA, Abiodun OO. 2007. Studies on antimicrobial, antioxidant and phytochemical analysis of Urena lobata leave extract. J. Phys. Nat. Sci. 1:12‑20.

      [2] Ali S, Faruq KO, Rahman AA, Hossain MA. 2013. Antioxidant and cytotoxic ativities of methanol extract of Urena lobata (L.) Leaves. Pharm. Innov. J. 2:9‑14.

      [3] Babu SS, Madhuri DB, Ali SL. 2016. A pharmacological review of Urena lobata plant. Asian J. Pharm. Clin. Res. 9:20-22.

      [4] Babu SS, Madhuri DB, Reddy DS. 2016. Anxiolytic antidepressant and anti-inflammatory activity of ethanolic extract of Urena lobata leaf. Int. J. Pharm. Res. Health Sci. 4:1284-1290. https://doi.org/10.21276/ijprhs.2016.04.07.

      [5] Dhanapal R, Ratna JV, Gupta M, Sarathchandran I. 2012. Preliminary study on antifertility activity of Enicostemma axillare leaves and Urena lobata root used in Indian traditional folk medicine. Asian Pac. J. Trop. Med. 5:616-622. https://doi.org/10.1016/S1995-7645(12)60127-8.

      [6] Eze SO, Ogbuefi RA. 2014. Analytical potentials of dye extracts from Urena lobata (Mgbo) flowers. Commun. Appl. Sci. 2:25‑35.

      [7] Gao XL, Liao Y, Wang J, Liu XY, Zhong K, Huang YN, Gao H, Gao B, Xu ZJ. 2015. Discovery of a potent anti-yeast triterpenoid saponin, clematoside-S from Urena lobata L. Int. J. Mol. Sci. 16:4731-4743. https://doi.org/10.3390/ijms16034731.

      [8] Islam H, Hasanur Rahman KM, Rahman S, Rahmatullah M. 2015. Preliminary antihyperglycemic, antinociceptive activity, phytochemical analysis and toxicity studies on leaves of Urena lobata L. J. Chem. Pharm. Res. 7:559‑563.

      [9] Islam MT, Freitas RM, Oliveira GLS, Guha B. 2014. Neuropharmacological screenings of hydroalcoholic fractions of Urena lobata L. World J. Pharm. Pharmaceut. Sci. 3:62-71.

      [10] Islam MT, Ibrahim M, Ahsan MQ, Chowdhury MMU, Hossain MA, Rashid MA. 2012. Phytochemical and Pharmacological Investigations of Uraria lagopodies DC. and Urena lobata L. Dhaka Univ. J. Pharm. Sci. 11:65-69. https://doi.org/10.3329/dujps.v11i1.12490.

      [11] Islam MT, Mata AMOF, Aguiar RPS, Paz MFCJ, de Alencar MVOB, de Melo-Cavalcante AAC. 2016. Therapeutic Potential of Essential Oils Focusing on Diterpens. Phytother. Res. 30:1420-1444. https://doi.org/10.1002/ptr.5652.

      [12] Jia L, A YM, Jing LL, Zhou SA, Kong DY. 2011. Three new flavonoid glycosides from Urena lobata. J. Asian Nat. Prod. Res. 13:907-914. https://doi.org/10.1080/10286020.2011.599802.

      [13] Jia L, Bi YF, Jing LL, Zhou SA, Kong DY. 2010. Two new compounds from Urena lobata L. J. Asian Nat. Prod. Res. 12:962-967. https://doi.org/10.1080/10286020.2010.510468.

      [14] Lissy KP, Simon TK, Lathab MS. 2006. Antioxidant potential of Sida retusa, Urena lobata and Triumfetta rhomboidea. Anc. Sci. Life 25:10-15.

      [15] Mathappan R, Umachigi SP, Prasanth VV. 2013. Wound healing activity of the methanolic extract of Urena lobata Linn. Int. J. Pharm. Chem. Sci. 2:793‑800.

      [16] Mazumder UK, Gupta M, Manikandan L, Bhattacharya S. 2001. Antibacterial activity of Urena lobata root. Fitoterapia 72:927-929. https://doi.org/10.1016/S0367-326X(01)00330-6.

      [17] Medicinal Plants of Bangladesh (MPB). 2017. Link: http://www.mpbd.info/plants/urena-lobata.php.

      [18] Morelli CF, Cairoli P, Speranza G, Alamgir M, Rajia S. 2006. Triglycerides from Urena lobata. Fitoterapia 77:296-299. https://doi.org/10.1016/j.fitote.2006.03.010.

      [19] Mshelia IY, Dalori BM, Hamman LL, Garba SH. 2013. Effect of the aqueous root extract of Urena lobata (Linn) on the liver of albino rat. Res. J. Appl. Sci. Eng. Technol. 5:1‑6.

      [20] Oladele GM, Abatan MO. 2010. Haematological and sperm count changes following exposure to Hyptis suaveolens, Cleome viscosa and Urena lobata in rats. Nig. Vet. J. 31:170‑176.

      [21] Omonkhua AA, Onoagbe IO. 2008. Effects of Irvingia grandifolia, Urena lobata and Carica papaya on the oxidative status of normal rabbits. Internet J. Nutr. Wellness 6:1-11.

      [22] Onoagbe IO, Negbenebor EO, Ogbeide VO, Dawha IH, Attah V, Lau HU, et al. 2010. A study of the anti‑diabetic effects of Urena lobata and Sphenostylis stenocarpa in streptozotocin‑induced diabetic rats. Eur. J. Sci. Res. 43:6‑14.

      [23] Pieme CA, Ngogang J, Costache M. 2012. In vitro antiproliferative and anti‑oxidant activities of methanol extracts of Urena lobata and Viscum album against breast cancer cell lines. Toxicol. Environ. Chem. 94:1‑13. https://doi.org/10.1080/02772248.2012.674135.

      [24] Sajem AL, Gosai K. 2006. Traditional use of medicinal plants by the Jaintia tribes in North Cachar Hills district of Assam, northeast India. J. Ethnobiol. Ethnomed. 2:1-7. https://doi.org/10.1186/1746-4269-2-1.

      [25] Purnomo Y, Soeatmadji DW, Sumitro SB, Widodo MA. 2016. Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells. J. Trad. Compl. Med. https://doi.org/10.1016/j.jtcme.2016.10.001.

      [26] Purnomo Y, Soeatmadji DW, Sumitro SB, Widodo MA. 2014. Po145 the comparison of activity dipeptidyl peptidase IV (DPP-IV) inhibitor between Urena lobata and Tithonia diversifolia leaf extract. Diabet. Res. Clin. Pract. 106:S121. https://doi.org/10.1016/j.jtcme.2016.10.001.

      [27] Yadav AK, Tangpu V. 2007. Antidiarrheal activity of Lithocarpus dealbata and Urena lobata extracts: Therapeutic implications. Pharm. Biol. 45:223‑229. https://doi.org/10.1080/13880200701213153.

      [28] Purnomo Y, Soeatmadji DW, Sumitro SB, Widodo MA. 2015. Anti-diabetic potential of Urena lobata leaf extract through inhibition of dipeptidyl peptidase IV activity. Asian Pac. J. Trop. Biomed. 5:645-649. https://doi.org/10.1016/j.apjtb.2015.05.014.

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    Islam, M., & Uddin, M. (2017). A revision on Urena lobata L. International Journal of Medicine, 5(1), 126-131. https://doi.org/10.14419/ijm.v5i1.7525