Vitamin A in prevention and treatment of cancer

 
 
 
  • Abstract
  • Keywords
  • References
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  • Abstract


    Dietary components not only act as chemo preventive agents but also risk factors in the onset of cancer, which stimulating nutritional bal-ance in cancer or non-cancer populations. The supplementation of antioxidant compounds, such as vitamin A (Vit A) and few of its deriva-tives has been reported to alleviate the oxidative stress in cancer patients. This review focuses on sketching a current scenario on the Vit A role in cancer prevention and therapy. Therefore, we searched for published article on PubMed and Science Direct between 2014 and 2015. The search yielded 75 articles related to Vit A-mediated anti-oxidative or pro-oxidative effects in cancer patients. A low dose-mediated anti-cancer effect was observed with Vit A in some cancers. The clinical studies showed discrepancies between the low and high doses of Vit A in cancer. In conclusion, precautions are needed in taking Vit A and its derivatives, especially in cancer.

  • Keywords


    : Vitamin A; Oxidative Stress, Cancer.

  • References


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Article ID: 7947
 
DOI: 10.14419/ijm.v5i2.7947




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